Hydroxylation Metabolisms of Crassicauline A in Rats Under Toxic Dose

ConclusionsThis work disclosed that crassicauline A is elimilated in rats predominantly by metabolism under toxic dosage and the hydroxylation probably at C-15 might be a potential bioactivation pathway in both rats and human.

Source: European Journal of Drug Metabolism and Pharmacokinetics - March 7, 2017 Category: Drugs & Pharmacology Source Type: research