What is myocarditis? Pop legend George Michael suffered from condition, coroner reveals
MYOCARDITIS is an inflammation of the myocardium, which is a heart muscle. A coroner has revealed pop legend George Michael died from the condition - dilated cardiomyopathy with myocarditis and fatty liver.
(University of Colorado Anschutz Medical Campus) In an effort to combat a growing worldwide epidemic of Nonalcoholic Fatty Liver Disease (NAFLD), scientists have discovered a new target and a new therapy that has shown promising results in preclinical mouse models, according to researchers at the University of Colorado Anschutz Medical Campus.
ConclusionsPositive ANA and ASMA are common in children with NAFLD; however, anti ‐LKM positivity is not. ANA positivity is associated with more severe steatosis.
Publication date: Available online 6 July 2020Source: Clinics and Research in Hepatology and GastroenterologyAuthor(s): Su Lin, Mingfang Wang, Yuxiu Liu, Jiaofeng Huang, Yinlian Wu, Yueyong Zhu, Xiaozhong Wang
Publication date: Available online 7 July 2020Source: Journal of Cardiology CasesAuthor(s): Adrienn Tünnemann-Tarr, Stephan Stöbe, Ulrich Laufs, Andreas Hagendorff, Bhupendar Tayal
In conclusion, the present study identified six hub genes related to DCM. Therefore, the present results may provide a potential mechanism for DCM involving these hub genes, which may serve as biomarkers for screening and diagnosis in the clinic. PMID: 32626989 [PubMed - as supplied by publisher]
Authors: Lin ZP, Lin HL, Yu XP, Zheng YJ, Cheng SY Abstract Obstructive sleep apnea syndrome (OSAS) is a common and complex disorder that is associated with liver injury. Moreover, previous studies have revealed that chronic intermittent hypoxia (CIH) is associated with the development of non‑alcoholic fatty liver disease and hepatic fibrosis. However, the underlying molecular mechanisms remain largely unknown. The present study aimed to investigate whether chronic intermittent hypoxia induced hepatic fibrosis, in addition to determining its underlying mechanisms, in CIH model rats using immunohistochemistry, wes...
CONCLUSIONS: The present study implied possible DEGs, especially the new gene CEP192, in the progression of NAFLD developing to HCC. Further rigorous experiments are required to verify the above results. PMID: 32623384 [PubMed - as supplied by publisher]
Authors: Lee WH, Chen YC, Chen SC, Chen CJ, Hsu PC, Tsai WC, Chu CY, Lee CS, Lin TH, Voon WC, Kuo CH, Su HM Abstract Based on clinical presentation, pathophysiology, high infectivity, high cardiovascular involvement, and therapeutic agents with cardiovascular toxicity of coronavirus disease 2019 (COVID-19), regular cardiovascular treatment is being changing greatly. Despite angiotensin-converting enzyme 2 serving as the portal for infection, the continuation of clinically indicated renin-angiotensin-aldosterone blockers is recommended according to the present evidence. Fibrinolytic therapy can be considered a reaso...
The objective of this study was to determine the association between elevated ALT in early pregnancy and the development of gestational diabetes or preeclampsia in late pregnancy. METHODS: In this retrospective cohort study, pregnant women who met the following inclusion criteria were included: 1) singleton pregnancy; 2) ALT levels were measured in antenatal outpatient clinic at 4-20 weeks of gestation; 3) patients were screened for gestational diabetes and delivered in Cheil General Hospital and Women's Healthcare Center. Cases with viral hepatitis or other liver diseases were excluded. The early ALT levels were divid...
Publication date: Available online 6 July 2020Source: Journal of Molecular StructureAuthor(s): De-Feng Cai, Yuan-Shan Lu, Zhi-Hao Xing, Hong-Yu Chen, Xiao-Rong Liu, Dong-Li Ma