New method rescues donor organs to save lives

Researchers have -- for the first time -- maintained a fully functional lung outside the body for several days. They designed the cross-circulation platform that maintained the viability and function of the donor lung and the stability of the recipient over 36-56 hours, used the advanced support system to fully recover the functionality of lungs injured by ischemia and made them suitable for transplant.
Source: ScienceDaily Headlines - Category: Science Source Type: news

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Transplant Infectious Disease, EarlyView.
Source: Transplant Infectious Disease - Category: Transplant Surgery Authors: Source Type: research
Authors: Lynch TJ, Ahlers BA, Parekh KR PMID: 30233912 [PubMed]
Source: Journal of Thoracic Disease - Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research
Authors: Ius F, Tudorache I, Warnecke G Abstract During recent years, continuous technological innovation has provoked an increase of extracorporeal life support (ECLS) use for perioperative cardiopulmonary support in lung transplantation. Initial results were disappointing, due to ECLS-specific complications and high surgical risk of the supported patients. However, the combination of improved patient management, multidisciplinary team work and standardization of ECLS protocols has recently yielded excellent results in several case series from high-volume transplant centres. Therein, it was demonstrated that, alth...
Source: Journal of Thoracic Disease - Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research
Authors: Panchabhai TS, Biswas Roy S, Madan N, Abdelrazek H, Patel VJ, Walia R, Bremner RM PMID: 30233886 [PubMed]
Source: Journal of Thoracic Disease - Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research
Publication date: October 2018Source: The Annals of Thoracic Surgery, Volume 106, Issue 4Author(s): Branden W. Luna, Luca Paoletti, Chadrick E. Denlinger, Nicholas J. Pastis, Timothy P. WhelanAirway complications after lung transplantation are well described and can lead to significant morbidity and mortality. Treatment options for anastomotic dehiscence include expectant management, placement of endobronchial stents, or surgical repair. The use of fibrin sealant instilled by bronchoscopy to seal a dehiscence has not been well described. Our patient is a 57-year-old man who underwent orthotropic bilateral lung tr...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
This study aimed to assess patterns of hepatocellular carcinoma (HCC) recurrence after liver transplantation (LT) and to establish long-term surveillance protocols for late HCC recurrence. MATERIAL AND METHODS The 232 LT recipients experiencing subsequent HCC recurrence were categorized as Group 1, early recurrence (within 1 year of LT; n=117); Group 2, late recurrence (occurring in years 2-5; n=93); and Group 3, very late recurrence (after year 5; n=22). RESULTS Recurrence was detected by only elevated tumor marker levels in 11.1%, 30.1%, and 45.5% of patients in Groups 1, 2, and 3, respectively (p
Source: Annals of Transplantation - Category: Transplant Surgery Authors: Tags: Ann Transplant Source Type: research
AbstractPurpose of ReviewConnective tissue disease-related interstitial lung disease (CTD-ILD) previously was a relative contraindication to lung transplantation primarily due to extra-pulmonary involvement of the disease. Recent published information focusing on the diagnosis and management of the extra-pulmonary complexities associated with CTD-ILD that challenge the success of lung transplantation indicate similar outcomes when compared to idiopathic causes of interstitial lung disease. Recent literature examining appropriate wait-listing criteria, disease management, and outcomes after lung transplantation are discusse...
Source: Current Respiratory Care Reports - Category: Respiratory Medicine Source Type: research
Almost exactly a year ago, Tiffany and Chuck Palmer were told to expect a stillborn baby. Now, their son is eight months, after getting both his heart and lungs replaced. And he is home in Kansas City.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Infection with the hepatitis C virus (HCV) has adverse liver, kidney, and cardiovascular consequences in patients with chronic kidney disease (CKD), including those on dialysis therapy and in those with a kidney transplant. Since the publication of the original Kidney Disease: Improving Global Outcomes (KDIGO) HCV Guideline in 2008, major advances in HCV management, particularly with the advent of direct-acting antiviral therapies, have now made the cure of HCV possible in CKD patients. In addition, diagnostic techniques have evolved to enable the noninvasive diagnosis of liver fibrosis.
Source: Kidney International - Category: Urology & Nephrology Authors: Tags: Guideline Summary Source Type: research
American Journal of Transplantation,Volume 0, Issue ja, -Not available-.
Source: American Journal of Transplantation - Category: Transplant Surgery Authors: Source Type: research
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