WT1 mutation-associated nephropathy: a single-center experience .
In conclusion, a high WT1 mutation rate was observed in this group of SRNS patients. Patients with splice-site mutations experienced a rapid disease progression, and patients harboring nonsense mutations showed a prominent glomerular developmental delay. CNI therapy was effective in patients with WT1 missense mutations and nonsense mutations.
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PMID: 28257282 [PubMed - as supplied by publisher]
Source: Clinical Nephrology - Category: Urology & Nephrology Authors: Yue Z, Wang H, Lin H, Yang J, Liu T, Liu Y, Chen H, Sun L Tags: Clin Nephrol Source Type: research
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