GSK-3 β inhibitor TDZD-8 reduces neonatal hypoxic-ischemic brain injury in mice.

CONCLUSION: TDZD-8 has the therapeutic potential for hypoxic-ischemic brain injury in neonates. The neuroprotective effect of TDZD-8 appears to be mediated through its antiapoptotic activity and by reducing astrogliosis.
PMID: 28256059 [PubMed - as supplied by publisher]

Source: CNS Neuroscience and Therapeutics - March 1, 2017 Category: Neuroscience Authors: Huang S, Wang H, Turlova E, Abussaud A, Ji X, Britto LR, Miller SP, Martinez A, Sun HS, Feng ZP Tags: CNS Neurosci Ther Source Type: research