Metabolic cardiomyopathies: fighting the next epidemic

Source: Cardiovascular Research - Category: Cardiology Source Type: research

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Publication date: Available online 22 February 2020Source: Microbes and InfectionAuthor(s): Jason A. TetroAbstractOne of the most perplexing questions regarding the current COVID-19 coronavirus epidemic is the discrepancy between the severity of cases observed in the Hubei province of China and those occurring elsewhere in the world. One possible answer is antibody dependent enhancement (ADE) of SARS-CoV-2 due to prior exposure to other coronaviruses. ADE modulates the immune response and can elicit sustained inflammation, lymphopenia, and/or cytokine storm, one or all of which have been documented in severe cases and deat...
Source: Microbes and Infection - Category: Infectious Diseases Source Type: research
The new Netflix documentary series profiles Dan Schneider, a small-town pharmacist who was one of the first people to identify and confront what we now know as America's opioid epidemic.
Source: Health News: CBSNews.com - Category: Consumer Health News Source Type: news
An explosive new Netflix documentary series shows how a Louisiana pharmacist was forced to face the opioid crisis head on after his son ’s death. His battle reveals some stunning facts about the crisis’ origins. Jamie Wax reports.
Source: Health News: CBSNews.com - Category: Consumer Health News Source Type: news
Today the MRC, theAcademy of Medical Sciences and the InterAcademy Partnership, publish the findings from a two-day meeting on epidemic preparedness held in October 2019.
Source: Medical Research Council General News - Category: Research Source Type: news
The contagion “represents a tremendous public health threat,” said one federal health official.
Source: NYT Health - Category: Consumer Health News Authors: Tags: your-feed-science Centers for Disease Control and Prevention State Department Coronavirus (2019-nCoV) United States Hubei Province (China) Infections Epidemics Source Type: news
Publication date: Available online 20 February 2020Source: The LancetAuthor(s): Marius Gilbert, Giulia Pullano, Francesco Pinotti, Eugenio Valdano, Chiara Poletto, Pierre-Yves Boëlle, Eric D'Ortenzio, Yazdan Yazdanpanah, Serge Paul Eholie, Mathias Altmann, Bernardo Gutierrez, Moritz U G Kraemer, Vittoria ColizzaSummaryBackgroundThe novel coronavirus disease 2019 (COVID-19) epidemic has spread from China to 25 countries. Local cycles of transmission have already occurred in 12 countries after case importation. In Africa, Egypt has so far confirmed one case. The management and control of COVID-19 importations heavily re...
Source: The Lancet - Category: General Medicine Source Type: research
China reported a sharp decrease in the number of new deaths and new cases of the coronavirus on Saturday, while its central bank predicted a limited short-term economic impact and said the country was confident of winning the fight against the epidemic.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
Publication date: Available online 20 February 2020Source: Microbes and InfectionAuthor(s): Xingchen Pan, David M. Ojcius, Tianyue Gao, Zhongsheng Li, Chunhua Pan, Chungen PanAbstractOnly a month after the outbreak of pneumonia caused by 2019-nCoV, more than forty-thousand people were infected. This put enormous pressure on the Chinese government, medical healthcare provider, and the general public, but also made the international community deeply nervous. On the 25th day after the outbreak, the Chinese government implemented strict traffic restrictions on the area where the 2019-nCoV had originated—Hubei province, w...
Source: Microbes and Infection - Category: Infectious Diseases Source Type: research
In this study, a kind of highly biocompatible CDs (Gly ‐CDs) is synthesized from active ingredient (glycyrrhizic acid) of Chinese herbal medicine by a hydrothermal method. Using the porcine reproductive and respiratory syndrome virus (PRRSV) as a model, it is found that the Gly‐CDs inhibit PRRSV proliferation by up to 5 orders of viral titers. Detai led investigations reveal that Gly‐CDs can inhibit PRRSV invasion and replication, stimulate antiviral innate immune responses, and inhibit the accumulation of intracellular reactive oxygen species (ROS) caused by PRRSV infection. Proteomics analysis demonstrates that Gly...
Source: Small - Category: Nanotechnology Authors: Tags: Full Paper Source Type: research
COVID-19, perhaps still better known as novel coronavirus, is a dangerous and rapidly spreading disease that governments and healthcare stakeholders are working around the world to contain. But how is new technology shaping the narrative of this epidemic, and is it making it easier to manage than previous outbreaks?
Source: mobihealthnews - Category: Information Technology Source Type: news
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