CXCR4 (CD184) Expression on Stem cell Harvest and CD34+ Cells Post-transplant
Conclusion SDF-1/CXCR4 axis plays a crucial role in engraftment; however, more studies are warranted to assess their expression post-transplant. Evaluating the ligand (chemokine, SDF-1) or its receptor (CXCR4) may serve as potential surrogate markers for assessment of engraftment.
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Condition: Hormone Deficiency Intervention: Combination Product: adipose-derived mesenchymal stem cells Sponsor: Vinmec Research Institute of Stem Cell and Gene Technology Recruiting
Condition: Chronic Myeloid Leukemia Intervention: Biological: Chronic Myeloid Leukemia + NK cell Sponsor: Hospital de Clinicas de Porto Alegre Enrolling by invitation
Condition: Acute Myeloid Leukemia Intervention: Drug: Minnelide Sponsors: Justin Watts; Minneamrita Therapeutics LLC Not yet recruiting
Condition: Osteochondral; Defect Interventions: Procedure: autologous osteo-periosteal cylinder graft transplantation; Procedure: autologous osteochondral graft transplantation Sponsor: Peking University Third Hospital Not yet recruiting
Conditions: Pregnancy Complications; Anemia, Iron Deficiency; H Pylori Infection Interventions: Drug: triple attack therapy; Drug: Ferrous(II)-glycine-sulphate complex 567.7 mg capsules Sponsor: Kasr El Aini Hospital Not yet recruiting
With a rise in the prevalence of chronic wounds and other soft tissue defects, there is an urgent need to regenerate skin. Multilineage-differentiating stress-enduring cells were identified as distinct pluripotent stem cells in mesenchymal cell populations in humans. New research demonstrates the ability to effectively differentiate multilineage-differentiating stress-enduring cells into fibroblasts and keratinocytes for skin reconstitution.
By genetically altering a patient ’ s T-cells to attack more than one site on cancer cells, researchers hope to devise better treatments.
Two doctors and a dentist from UCLA have been selected as 2017 fellows of the American Association for the Advancement of Science. They are among 396 members awarded this honor by the AAAS for their scientifically or socially distinguished efforts to advance science or its applications.New fellows will be presented with an official certificate and a gold and blue rosette pin, representing science and engineering, on Feb. 17, 2018, at the association ’s annual meeting in Austin, Texas, and formally announced in the “AAAS News and Notes” section of the journal Science on Nov. 24.UCLA ’...
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