57: evaluation of the circulating levels of il-12 and il-33 in patients with breast cancer: influences of the tumor stages and cytokine gene polymorphisms

Conclusion: These results indicate that the diminished IL-12 production may contribute to the tumor establishment. The higher IL-33 levels and IL-33/IL-12 ratio in patients also indicate an imbalance in Th1/Th2 responses that may contribute to tumor development. Thus, correcting the imbalance of Th1/Th2 could be an important strategy for cancer immunotherapy.
Source: BMJ Open - Category: Journals (General) Authors: Tags: Open access Poster Source Type: research