Impact of 18F-Fluciclovine PET on Target Volume Definition for Postprostatectomy Salvage Radiotherapy: Initial Findings from a Randomized Trial

Conclusion: Including information from 18F-fluciclovine PET in the treatment-planning process led to significant differences in the defined target volume, with higher doses to the penile bulb but no significant differences in rectal or bladder dose or in acute genitourinary or gastrointestinal toxicity. Longer follow-up is needed to determine the impact of 18F-fluciclovine PET on cancer control and late toxicity endpoints.

Source: Journal of Nuclear Medicine - February 28, 2017 Category: Nuclear Medicine Authors: Jani, A. B., Schreibmann, E., Rossi, P. J., Shelton, J., Godette, K., Nieh, P., Master, V. A., Kucuk, O., Goodman, M., Halkar, R., Cooper, S., Chen, Z., Schuster, D. M. Tags: Clinical Source Type: research