Colorectal Cancer Rates Are Rising Sharply Among Young Americans

This study didn’t measure why colorectal cancer was rising in younger people, but the scientists did dive into past research on the subject to came up with a few theories.  Colorectal cancer risk is linked to excess body weight, cigarette smoking and the consumption of lots of alcohol and highly processed meat. At the same time, eating little fiber and a sedentary lifestyle are also linked to a higher risk of colorectal cancer. While it’s true that younger generations smoke and drink less than baby boomers, they also weigh more, and at younger ages. This prolonged obesity could be a clue, Siegel and her colleagues write.  “It is not surprising that the timing of the obesity epidemic parallels the rise in [colorectal cancer] because many behaviors thought to drive weight gain, such as unhealthy dietary patterns and sedentary lifestyles, independently increase [colorectal cancer] risk.” And beyond just weight gain, Siegel pinpoints the kinds of foods that might contribute to higher cancer rates and are more prevalent today than they were a few generations ago: high-glycemic load carbohydrates like sugar, honey, candy, white bread, pastries and packaged breakfast cereals. In addition to questions on the possible cause of this cancer rise, the research also raised questions about if and how screening recommendations should change to help younger people avoid colorectal cancer, said Dr. Darrell Gray II, a gastroenterologist at Ohio State Universit...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

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ABSTRACT: The lifelong, chronic nature of Crohn's disease produces incessant stress that affects individuals physically, emotionally, and socially. Coping with the symptoms and treatment is improved when persons engage their faith and spiritual resources. Clear understanding of the physical and emotional aspects of Crohn's can support a person's ability to manage the disease. Knowledge of emerging treatments also provides nurses with hopeful input to share with their patients.
Source: Journal of Christian Nursing - Category: Nursing Tags: JCN Online Extra: online only: practice Source Type: research
Authors: Bratu OG, Diaconu CC, Mischianu DLD, Constantin T, Stanescu AMA, Bungau SG, Ionita-Radu F, Marcu RD Abstract Prostate cancer is the second most common form of cancer in men in Europe. The primary treatment of this type of cancer is radical prostatectomy, which has shown good oncological results. Radical prostatectomy (open, laparoscopic or robotic) has high success and low morbidity rates in patients with localized prostate cancer. The life expectancy is>10 years after radical prostatectomy. Studies have shown that ~20%-30% of the patients who have undergone radical prostatectomy can develop biochemical...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Aspects concerning patient adherence to anti-TNFα therapy in psoriasis: A decade of clinical experience. Exp Ther Med. 2019 Dec;18(6):4987-4992 Authors: Mocanu M, Toader MP, Rezus E, Taranu T Abstract Non-adherence to psoriasis treatment has an important impact in controlling chronic disease evolution and the occurrence of systemic comorbidities. Biologic therapy represents a revolutionary treatment, many of the undesirable psychological and socio-economical consequences of conventional topical or systemic therapies being avoided. Nevertheless, the discontinuation of biological therapy may occur ...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Authors: Liu Z, Xie W, Li M, Liu J, Liang X, Li T Abstract Polaprezinc (PZ), a chelate of zinc and L-carnosine, has been widely used in the treatment of gastric ulcers since 1994. In recent years, researchers have found PZ to have a beneficial effect on various experimentally induced models of colitis in mice. In the present study, 6% dextran sodium sulfate (DSS) was used to induce a model of ulcerative colitis (UC) in Institute of Cancer Research mice. The therapeutic effect and mechanism of PZ action in a model of UC was studied in order to provide an experimental basis for the clinical application of PZ in UC tr...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Authors: Shen H, Liao K, Wu W, Yu H, Wu H Abstract A total of six male patients, who had undergone radical cystectomy and sigma-rectum pouch surgery due to bladder cancer (2-5 years previously), developed hyperchloremic metabolic acidosis, hypokalemia and renal dysfunction. The patients underwent urinary undiversion surgery (the pouch was isolated from the intestinal tract, abdominal ostomy was performed, and the sigmoid colon and rectum were reconnected) and blood gas and electrolyte analysis and renal function were compared pre- and post-surgery. Blood hydrocarbonate levels significantly improved 3 months post-su...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
In conclusion, the present study indicated that endovascular treatment is a safe and efficient method for patients with vertebral artery aneurysm. The treatment strategy should be based on the patient's condition and aneurysmal characteristics. Parent artery occlusion may be suitable for selected patients with ruptured vertebral artery aneurysms. PMID: 31798709 [PubMed]
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
In conclusion, under normoxic conditions, lactate exerted a weak effect on macrophages, while the combination of lactate and hypoxia markedly promoted the M2-polarization of macrophages via the HIF-1, Hedgehog and mTOR pathways. Lactate and hypoxia may also contribute to the formation of the spatial structure of tumor niches by inhibiting the proliferation of resident macrophages and by regulating the recruitment of peripheral macrophages. PMID: 31798707 [PubMed]
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Authors: Zhang Y, Ma L, Fu Q, Zhao T, Yan RY, Su X Abstract Thrombolytic treatment is recommended for patients with high-risk pulmonary embolism. The present study compared thrombolytic therapy with urokinase and reteplase. A total of 37 patients presenting with acute high-risk pulmonary embolism at the Intensive Care Unit of Weinan Central Hospital of Shaanxi Province (Weinan, China) between June 2013 and January 2017 were retrospectively analyzed. According to their treatment, these subjects were assigned to the reteplase group (n=16) or the urokinase group (n=21). Systolic blood pressure (SBP), heart rate (HR) a...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Authors: Yang H, Wang Y, Gao J, Wang P, Jiang X, Tian D, Hu H Abstract A 67-year-old male patient had a history of repeated urinary tract infections for numerous years. X-ray examination revealed a large calcific density in the pelvic cavity, with a diameter of 10.4 cm and a CT value of ~792.9 HU. On MRI of the pelvis, the lesion displayed with extremely low signals. The inside of the stone had a concentric ring shape with a slightly higher signal and the patient was diagnosed with a large left seminal vesicle calculus. Laparoscopic surgery was selected to treat the stone. The patient recovered rapidly and the symp...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Authors: Wang W, Zhang L, Wang X, Lin D, Pan Q, Guo L Abstract Pioglitazone, a type of insulin sensitizer, serves as an effective anti-hyperglycemic drug. The mechanism of action of pioglitazone is through the activation of the peroxisome proliferator-activated receptor (PPAR), which results in enhanced insulin sensitivity of peripheral tissues and the liver, causing a reduction in the production and output of liver sugar. It has been reported that pioglitazone increases the risk of bladder cancer, but the underlying mechanisms have remained elusive. It was hypothesized that modulation of pioglitazone activity may ...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
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