Abstract P2-07-06: Obesity, dyslipidemia, and diabetes as risk factors for trastuzumab-related cardiotoxicity in breast cancer patients

Conclusions: This cohort study describes the clinical appearance and prognosis of CNS metastases in breast cancer pts during a seven years period in the institution treating all pats in the County of Uppsala. Distinctive clinical differences between the breast cancer subtypes could be noticed which possible represents different mechanism in the metastatic process as well as different treatment response. The survival in the luminal subgroups was short and CNS met developed considerably later in the course of the disease when pts might have developed a more aggressive and therapy resistant disease.Citation Format: Aseyev O, Johnson C, Turek M, Stadnick E, Law A, Gosh N, Dent S. Obesity, dyslipidemia, and diabetes as risk factors for trastuzumab-related cardiotoxicity in breast cancer patients [abstract]. In: Proceedings of the Thirty-Ninth Annual CTRC-AACR San Antonio Breast Cancer Symposium; 2016 Dec 6-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2017;77(4 Suppl):Abstract nr P2-07-06.

Source: Cancer Research - February 13, 2017 Category: Cancer & Oncology Authors: O Aseyev, C Johnson, M Turek, E Stadnick, A Law, N Gosh, S Dent Tags: Poster Session Abstracts Source Type: research