Cytotoxicity and genotoxicity of a low-shrinkage monomer and monoacylphosphine oxide photoinitiator: Comparative analyses of individual toxicity and combination effects in mixtures

Residual monomers and other unbound substances from resin-based composites (RBCs) may reduce biocompatibility of RBCs via direct contact with oral tissues. Unbound components of composites diffuse through dentin into the pulp or elute into the oral cavity [1,2]. These substances may also be systemically distributed throughout the organism, either being taken up by circulating blood or swallowed by saliva, consequently causing adverse systemic effects [3,4].

Source: Dental Materials - February 27, 2017 Category: Materials Science Authors: Dragica Manojlovic, Miroslav D. Drami ćanin, Vesna Miletic, Dragana Mitić-Ćulafić, Bojana Jovanović, Biljana Nikolić Source Type: research