Medical News Today: Ketogenic diet may protect against gout

Could the low-carb, high-fat diet be helpful in treating the symptoms of gout? A new study investigates how the diet affects rodents and humans.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Gout Source Type: news

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Publication date: October 2019Source: Phytochemistry, Volume 166Author(s): Bao-Bao Shi, Jing Chen, Mei-Fen Bao, Ying Zeng, Xiang-Hai CaiAbstractContinued interest in bioactive alkaloids led to the isolation of four undescribed alkaloids along with 74 known ones from the aerial parts of Tabernaemontana bufalina Lour. The structures of the yet undescribed alkaloids were elucidated based on NMR, IR, UV, MS and CD spectroscopic data and X-ray crystal diffraction and, according to the plant source, named as taberhaines A–D (1–4). The known compounds comprised of 66 monoterpenoid indole, three carboline and five isoq...
Source: Phytochemistry - Category: Chemistry Source Type: research
Source: FDA Drug Safety Podcasts - Category: Drugs & Pharmacology Authors: Source Type: podcasts
Source: FDA Drug Safety Podcasts - Category: Drugs & Pharmacology Authors: Source Type: podcasts
Footwear is an important concern for people with gout, who often describe difficulty finding suitable footwear. Previous studies have identified footwear as a major concern for people with gout. The aim of thi...
Source: Journal of Foot and Ankle Research - Category: Podiatry Authors: Tags: Research Source Type: research
Nearly three in 10 patients seeking care at the emergency department (ED) for acute gout will be discharged with a prescription for opioids, new research shows.Reuters Health Information
Source: Medscape Orthopaedics Headlines - Category: Orthopaedics Tags: Rheumatology News Source Type: news
PMID: 31297604 [PubMed - as supplied by publisher]
Source: Zeitschrift fur Rheumatologie - Category: Rheumatology Authors: Tags: Z Rheumatol Source Type: research
ConclusionsIn the presence of elevated urate, human cartilage homogenates increase MSU crystal formation and promote the formation of smaller crystals which have greater inflammatory potential. These processes may contribute to the predilection of gout to osteoarthritic joints.This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatology - Category: Rheumatology Authors: Tags: Full Length Source Type: research
Source: Cardiovascular Intervention and Therapeutics - Category: Cardiology Source Type: research
NEW YORK (Reuters Health)—Nearly three in 10 patients seeking care at the emergency department (ED) for acute gout will be discharged with a prescription for opioids, new research shows. “Our study suggests a high use of prescription opioid in patients discharged from the ED with a diagnosis of gout, a condition that can be managed... [Read More]
Source: The Rheumatologist - Category: Rheumatology Authors: Tags: Conditions Crystal Arthritis Arthritis Care & Research Emergency Department Gout opioid Pain Pain Management Source Type: research
Lesinurad (systematic name: 2-{[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid, C17H14BrN3O2S) is a selective uric acid reabsorption inhibitor related to gout, which exhibits poor aqueous solubility. High-throughput solid-form screening was performed to screen for new solid forms with improved pharmaceutically relevant properties. During polymorph screening, we obtained two solvates with methanol (CH3OH) and ethanol (C2H5OH). Binary systems with caffeine (systematic name: 3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione, C8H10N4O2) and nicotinamide (C6H6N2O), polymorphs with urea (CH4N2O...
Source: Acta Crystallographica Section C - Category: Chemistry Authors: Tags: lesinurad uric acid reabsorption inhibitor cocrystal disappearing polymorph DFT solubility studies crystal structure powder diffraction research papers Source Type: research
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