Ethyl Pyruvate Attenuates Early Brain Injury Following Subarachnoid Hemorrhage in the Endovascular Perforation Rabbit Model Possibly Via Anti-inflammation and Inhibition of JNK Signaling Pathway.

In conclusion, the present study supported that EP afforded neuroprotective effects possibly via reducing TNF-α expression and inhibition of the JNK signaling pathway. Therefore, EP may be a potent therapeutic agent to attenuate EBI following SAH. PMID: 28236213 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/28236213?dopt=Abstract

Source: Neurochemical Research - February 24, 2017 Category: Neuroscience Authors: Lv T, Miao YF, Jin YC, Yang SF, Wu H, Dai J, Zhang XH Tags: Neurochem Res Source Type: research