Extremis Documentary Falls Short at Oscars, Wins Over Palliative Care

by Christian SinclairLast night at the Oscars, there sure was a lot of excitement for many of my friends and colleagues, and I'm not just talking about the surprise ending with La La Land winning Best Picture, then losing it in a tragic mistake of envelopes, to another well-deserving film Moonlight. That is because many of my friends and colleagues are strong advocates and wonderful clinicians who are vocal about excellent care at the end of life.The filmExtremis, which was released in April 2016 at the Tribeca Film Festival, was nominated for An Academy Award for Best Documentary Short Subject, but up against top competition did not end up taking home the Oscar. The winner last night was a film about the Syrian Civil Defense volunteer rescue workers calledThe White Helmets. The nomination forExtremis should really be considered a win, because now many more people are aware of it, and palliative care providers can use it as a discussion tool.Extremis offers a glimpse into the hectic and fragmented world of the Intensive Care Unit and the decisions doctors, patients and families make when the chances of survival reach the limits. The clinician who we follow isDr. Jessica Zitter, a Critical Care Specialist and board-certified palliative care physician.We see glimpses of her conversations with a diverse group of patients and families, never lingering on one discussion too long. Many phrases will feel familiar to palliative care and ICU staff as hope, miracles, uncertainty, and s...
Source: Pallimed: A Hospice and Palliative Medicine Blog - Category: Palliative Care Tags: extremis film sinclair zitter Source Type: blogs

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Source: Revue des Maladies Respiratoires - Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research
AbstractLocally advanced oral cancers extending to infratemporal fossa (ITF) are a challenge to head and neck surgeons. These tumors are classified as T4b whenever the masticator space (MS), pterygoid muscles (PM), and pterygoid plates (PP) are involved according to AJCC classification. Until recently, these tumors were considered inoperable and treated only with palliative intent. However, a few studies in the last decade showed that many of these tumors could be resected with a reasonably favorable prognosis by compartment resection of ITF, particularly when the tumor was below sigmoid notch of mandible. A few studies at...
Source: European Archives of Oto-Rhino-Laryngology - Category: ENT & OMF Source Type: research
We report a case of a 66-year-old woman with primary mediastinal LCNEC who presented with superior vena cava syndrome. Emergent radiotherapy was performed, followed by systemic chemotherapy with cisplatin and etoposide, which resulted in a dramatic tumor reduction. This is the first report describing the achievement of a complete response after systemic chemotherapy in a patient with primary LCNEC. PMID: 30333385 [PubMed - as supplied by publisher]
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
Most patients with metastatic germ-cell cancer (GCC) can be cured by cisplatin-based combination chemotherapy. Yet, about 10-15% of metastatic GCC patients will eventually die of their disease. This narrative review focuses on treatment options when cure is no longer realistic.
Source: Cancer Treatment Reviews - Category: Cancer & Oncology Authors: Tags: Tumour Review Source Type: research
Palliative radiotherapy (PRT) can relieve symptoms and improve quality of life, but remains underutilised, possibly due to lack of referrals. We conducted a systematic review to study barriers impeding referral for PRT.
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AbstractBackgroundStatins are often discontinued in patients with advanced cancer since the net effect of treatment is considered negative. However, guidelines concerning discontinuation of statin treatment are lacking. The aim of this study was to investigate any differences in time of discontinuation of statin treatment between men and women with advanced cancer disease.MethodsMedical records from 195 deceased palliative cancer patients from a previous study cohort were reviewed. Patients treated with statins 2  years before death were identified as “statin users.” The time of discontinuation of statin t...
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Condition:   Cancer Interventions:   Combination Product: Palliative care;   Combination Product: Standard oncological care Sponsor:   Yale University Not yet recruiting
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To paraphrase Bill Gates: “The purpose of humanity is not just to sit behind a counter and do things. More free time is not a terrible thing.” I have innovated. I developed a mutation assay. I discovered that vacuum ultraviolet light from excimer lasers is safe to use on human tissue. I invented an imaging device to detect burn wound depth and discovered the best laser to debride burn wounds. I invented a laser-based treatment for acne. I developed and patented an online gamified collective intelligence solution to identify dermatology images. I have participated and published as a clinician in numerous populat...
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Cutaneous squamous cell carcinoma (SCC) has the clinical and molecular features of a tumor that is likely to respond to systemic immunotherapy, as this tumor harbors a high mutational load and incidence is increased in immunocompromised patients. While nearly all cases are cured with surgery, in the remaining 5%, the tumor becomes metastatic or locally advanced, requiring palliative systemic therapy due to a lack of efficacious approved systemic therapies. In early phase I trials, the human monoclonal antibody to programmed death-1 (PD-1), cemiplimab, elicited a durable response in patients with advanced disease.
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End-of-life care (EoLC) is an experience that touches the lives of everyone. Dying in an acute hospital is a common occurrence in developed countries across the world. Previous studies have shown that there is...
Source: BMC Palliative Care - Category: Palliative Care Authors: Tags: Research article Source Type: research
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