Rapamycin Enhances Repressed Autophagy and Attenuates Aggressive Progression in a Rat Model of IgA Nephropathy.

CONCLUSION: These results may suggest that mTOR-mediated autophagy inhibition may result in mesangial cell proliferation in IgAN.
PMID: 28237991 [PubMed - as supplied by publisher]

Source: American Journal of Nephrology - February 24, 2017 Category: Urology & Nephrology Authors: Liu D, Liu Y, Chen G, He L, Tang C, Wang C, Yang D, Li H, Dong Z, Liu H Tags: Am J Nephrol Source Type: research