The Future of Intravascular Imaging: Are We Primed to Detect Vulnerable Plaques?

AbstractPurpose of ReviewAtherosclerotic plaque rupture remains the primary mechanism resulting in myocardial infarction and death. Better detection of the vulnerable atherosclerotic plaque, one which is at “high risk” of rupturing, will allow earlier and more effective intervention to preventing myocardial infarction in susceptible patients. In the following manuscript, we review recent developments in the assessment of vulnerable plaque via invasive imaging. The evidence, limitations, and future prospects of various intravascular imaging modalities (optical coherence tomography (OCT), intravascular ultrasound (IVUS), angioscopy, and near-infrared spectroscopy (NIRS)) are summarized.Recent FindingsThe vulnerable plaque has unique signature depending on the imaging modality used in the diagnostic process. We show illustrative examples from every modality and we shed light on emergent technologies, aiming at providing the reader with an understanding of the interaction between modalities. We also present the concept of three-dimensional plaque assessment and explore the role of invasive imaging in helping to understand the most recently identified mechanism of stent failure: neoatherosclerosis.SummaryAs all these invasive imaging modalities have proven to be safe and feasible, recent efforts have focused on software development aiming at increasing the ease of use of these technologies, allowing faster and more accurate online display of images, and one can forecas...
Source: Current Cardiovascular Imaging Reports - Category: Radiology Source Type: research

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Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
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Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
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Source: IJC Heart and Vasculature - Category: Cardiology Source Type: research
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Source: Cardiology Journal - Category: Cardiology Authors: Tags: Cardiol J Source Type: research
Intravascular imaging (intravascular ultrasound, IVUS and optical coherence tomography, OCT) are recommended tools to optimize stent placement during percutaneous coronary intervention (PCI).1 The use of intravascular imaging is increasing among patients undergoing PCI for non-ST elevation myocardial infarction (NSTEMI).2 Data on temporal trends of intravascular imaging use in the setting of ST elevation myocardial infarction (STEMI) are unknown. We performed this study to analyze trends of intravascular imaging for PCI in setting of STEMI.
Source: The American Journal of Cardiology - Category: Cardiology Authors: Source Type: research
Condition:   ST Elevation Myocardial Infarction Interventions:   Procedure: IVUS-guided PCI;   Procedure: Angiography-guided PCI Sponsors:   Second Affiliated Hospital, School of Medicine, Zhejiang University;   Ningbo No. 1 Hospital Not yet recruiting
Source: - Category: Research Source Type: clinical trials
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Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
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