FDA Expands Approval of Spiriva Respimat (tiotropium bromide) Inhalation Spray for Maintenance Treatment of Asthma in Children

RIDGEFIELD, Conn., February 16, 2017 - Boehringer Ingelheim Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration (FDA) approved Spiriva Respimat for the long-term, once-daily maintenance treatment of asthma in people age...
Source: Drugs.com - New Drug Approvals - Category: Drugs & Pharmacology Source Type: news

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Asthma is a global disease, but its impacts aren't
Source: Forbes.com Healthcare News - Category: Pharmaceuticals Authors: Source Type: news
Publication date: Available online 9 October 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Sande O. Okelo, Andrew L. Bilderback, Maria Fagnano, Jill S. Halterman
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
This study aimed to explore the predictors of bronchiolitis developing into asthma. MATERIAL AND METHODS The methylation status of RUNX3 promoter was assessed using Illumina HiSeq platform method. The relative RUNX3 mRNA levels in PBMCs were measured by qRT-PCR. Serum IL-4 and IFN-γ concentrations were measured by ELISA. RESULTS A series of sites with significantly higher levels of methylation as compared to their corresponding controls were identified, including 24 sites in group Ba vs. group Cn, 13 sites in group Ba vs. group Ca, 7 sites in group Ba vs. group Bn, 16 sites in group Bn vs. group Cn, 11 sites in group...
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
Among 6.1 million children with asthma, 38% have uncontrolled asthma leading to increased pediatric emergency department (ED) visits, hospitalizations, and healthcare costs. Uncontrolled asthma unequally harms children from lower-income, racial and ethn...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
We present this as a unique diagnostic clue for EGPA.
Source: The American Journal of Dermatopathology - Category: Pathology Tags: Extraordinary Case Report Source Type: research
Conclusions: In prematurely born children, there is a moderate association between severe RSV infection, as measured by RSV-H in the first year of life, and asthma up to 5 years of age.
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: Immunology and Host Response Source Type: research
Conclusions: It was estimated that the economic impact of a severe exacerbation in Spanish patients with severe asthma was €758.7/exacerbation. PMID: 31621441 [PubMed - as supplied by publisher]
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
Conclusions: No consistent differences between groups were found, suggesting that trained patients did not benefit from asthma education regarding HL and eHL. The 6-item and 16-item versions of the HLS-EU were not easily interchangeable, limiting its use in a busy outpatient practice. Abbreviations eHEALS Electronic Health Literacy Scale eHL Electronic Health Literacy HLS-EU European Health Literacy Survey. PMID: 31621438 [PubMed - as supplied by publisher]
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
Authors: Paraskevaidou K, Porpodis K, Kontakiotis T, Kioumis I, Spyratos D, Papakosta D Abstract Objective: The detection of asthma and rhinitis in furniture workers exposed to chemicals in the area of Thessaloniki Greece and the determination of the most useful tests for diagnosing the above occupational diseases. Methods: Eighty-three workers (76 men), 35 exposed to chemicals (CW), 23 to wood dust (WW), and 25 office workers (OW), serving as controls, filled in a specialized European Community Respiratory Health Survey (ECRHS) questionnaire for asthma and were submitted to clinical evaluation, spirometry, broncho...
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
Publication date: Available online 17 October 2019Source: Physiology &BehaviorAuthor(s): Kerry C. Michael, Robert H. Bonneau, Rebecca A. Bourne, LaDara Godbolt, Michael J. Caruso, Christine Hohmann, Sonia A. CavigelliAbstractStable behavioral traits (temperament, personality) often predict health outcomes. Temperament-specific differences in immune function could explain temperament-specific health outcomes, however, we have limited information on whether immune function varies by personality. In the present study, we examined the relationship between a basic behavioral trait (behavioral-inhibition vs. non-inhibition) ...
Source: Physiology and Behavior - Category: Physiology Source Type: research
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