Chemometric Study of Retention Indices of Some Thiazolidinediones Derivatives in Two Low Polarity Stationary Phases.

Chemometric Study of Retention Indices of Some Thiazolidinediones Derivatives in Two Low Polarity Stationary Phases.
Comb Chem High Throughput Screen. 2014 May 8;
Authors: Smolinski A, Djakovic-Sekulic TL
Abstract
Application of chemometric methods in the study of the retention indices of thirteen 5-arylidene-2,4-thiazolidinediones in two low polarity high-performance thin-layer chromatographic (HPTLC) stationary phases (RP-18 and RP-CN) and six aqueous mobile phases. Principal component analysis classified chromatographic systems into four specific groups while one system remained non-classified. Hierarchical clustering analysis enabled grouping of the chromatographic systems into three clusters, and the studied compounds into three main classes. The color map enabled more in-depth interpretation of the relationships between the studied compounds and HPTLC systems applied.
PMID: 24813247 [PubMed - as supplied by publisher]

Source: Combinatorial Chemistry and High Throughput Screening - May 8, 2014 Category: Chemistry Authors: Smolinski A, Djakovic-Sekulic TL Tags: Comb Chem High Throughput Screen Source Type: research