Scientists test deep brain stimulation as potential anorexia therapy

(Reuters) – A small study in 16 people with severe anorexia has found that implanting stimulation electrodes into the brains of patients could ease their anxiety and help them gain weight. Researchers found that in extreme cases of the eating disorder, the technique – known as deep brain stimulation (DBS) – swiftly helped many of those studied reduce symptoms of either anxiety or depression, and improved their quality of life. A few months later, the improved psychological symptoms began to lead to changes in weight, the researchers said, with the average body mass index (BMI) of the group increasing to 17.3 – a rise of 3.5 points – over the course of the study. Anorexia is a serious eating disorder that affects around 0.5 percent of people worldwide, the majority of them teenage girls. Patients have persistent concerns about their weight, shape and size, and starve themselves to maintain a low weight. Chronic anorexia can be fatal, and in many cases causes severe health problems including weak bones and muscles, sexual problems, infertility, heart problems and seizures. The scientists who led this study, published in The Lancet Psychiatry journal on Friday, said their results suggest deep brain stimulation – which involves implanting electrodes to stimulate brain areas that control dysfunctional behaviors – might alter the brain circuits that drive anorexia. DBS is already used to target brain circuits involved in Parkinson’s d...
Source: Mass Device - Category: Medical Equipment Authors: Tags: Neurological Source Type: news

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In this report, a 16-year-old boy presented with jaundice, nausea, vomiting and reduced urine output. He developed severe acute renal/hepatic damage due to abuse of gas products. Since toluene is the main toxic agent involved in glue sniffing which is metabolized to hippuric acid, the present case was treated with continuous hemodiafiltration, plasma exchange and conservative therapy to eliminate hippuric acid. The jaundice gradually disappeared, he had complete recovery of renal/hepatic functions in ten days. We aimed to increase the awareness among emergency physicians that ``glue sniffing` should be considered in the di...
Source: The Turkish Journal of Pediatrics - Category: Pediatrics Authors: Tags: Turk J Pediatr Source Type: research
This study presented 31 of 100 children needed further diagnostic work up and early intervention. Therefore, pediatricians should not underestimate speech delay. On the other hand, due to the fact that, the regulations to receive special education and therapy often create anxiety for the parents, we think that this system needs to be updated and special education support should be determined by the special needs of each child. PMID: 30325123 [PubMed - in process]
Source: The Turkish Journal of Pediatrics - Category: Pediatrics Authors: Tags: Turk J Pediatr Source Type: research
Authors: Tofte A, Narang P, Lippmann S PMID: 30326187 [PubMed - in process]
Source: The Primary Care Companion for CNS Disorders - Category: Primary Care Tags: Prim Care Companion CNS Disord Source Type: research
Conclusions: In general, the results from the reviewed studies suggest that BTA may be a promising treatment for MDD. However, these findings need to be interpreted with caution due to several limitations of the reviewed studies such as lack of a priori hypotheses, limited sample sizes, large gender bias, and significant difficulty in ensuring blinding. PMID: 30326186 [PubMed - in process]
Source: The Primary Care Companion for CNS Disorders - Category: Primary Care Tags: Prim Care Companion CNS Disord Source Type: research
If you break your foot and need an x-ray, you are much more likely to be directed to the Department of Diagnostic Imaging than to the Radiology Department. Forward-thinking radiology departments now like to include “imaging” in their titles. It captures the trajectory of growth away from the classic Roentgen ray of 1895 into a boundless visual universe comprised of bits and bytes. Workhorse computed tomography (CT) scans are yielding ground to a complex stew of ultrasound, magnetic resonance, and molecular and nuclear imaging-based technologies, all readily accessible on-screen in just a few clicks.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: Introduction Source Type: research
To the Editor: Central nervous system pathologic and normal anatomy have long been regarded as essentially static when planning treatment —motion management was thought to be unimportant because physiologic processes such as respiration or peristalsis do not affect intracranial anatomy. Indeed, 3-dimensional rigid registrations between magnetic resonance imaging (MRI) and computed tomography (CT) scans can be carried out with high d egrees of accuracy over months and years to permit the re-establishment of stereotactic coordinates for guidance and monitoring (1).
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: Determining Disease Extent Source Type: research
AbstractSoft-tissue sarcomas pose diagnostic and therapeutic challenges to physicians, owing to the large number of subtypes, aggressive tumor biology, lack of consensus on management, and controversy surrounding interval and duration of surveillance scans. Advances in multidisciplinary management have improved the care of sarcoma patients, but controversy remains regarding strategies for surveillance following definitive local control. This review provides an updated, comprehensive overview of the current understanding of the risk of local recurrence of soft-tissue sarcoma, by examining the literature based on features su...
Source: Skeletal Radiology - Category: Radiology Source Type: research
Publication date: Available online 17 October 2018Source: Social Science &MedicineAuthor(s): Claire Snell-Rood, Elizabeth Carpenter-SongAbstractPeople with mental illness face public scrutiny that provokes questions about their ability to cope, membership in society, and entitlement to state support. Less attention has been focused on how such scrutiny occurs at the community level, particularly when shared economic distress has generated a high burden of poor mental health. We employ theorizations of health-related deservingness to examine the local moral economies through which residents of an economically depressed ...
Source: Social Science and Medicine - Category: Psychiatry & Psychology Source Type: research
Authors: Sun W, Sun L, Yang F, Zhao X, Cai R, Yuan W Abstract OBJECTIVE: Cardiovascular magnetic resonance imaging (CMR) has been established as a modality to detect myocardial viability. The aim of this study was to evaluate myocardial viability by observing transmural extent of infraction and microvascular perfusion level. METHODS: We performed CMR in 30 myocardial infarction (MI) patients within 7-10 days. At the 6‑month follow-up, CMR was used to evaluate the impact of abnormal reperfusion and observe the transmural extent of infraction on recovery of function. RESULTS: The left ventric...
Source: Herz - Category: Cardiology Tags: Herz Source Type: research
You're reading 4 Bestselling Authors Share Their 4 Most Favorite Success Tips, originally posted on Pick the Brain | Motivation and Self Improvement. If you're enjoying this, please visit our site for more inspirational articles. Bestselling authors; Jordan Peterson, Jen Sincero, Mark Divine and Brad Gilbert share their four favorite success tips. Here they are… Success Tip#1: Treat yourself like you treat your dog (Assuming you`re not some animal-abusing psycho” “People appear to love their dogs, cats, ferrets, and birds (and maybe even their lizards) more than themselves. How horrible is that? How much...
Source: PickTheBrain | Motivation and Self Improvement - Category: Consumer Health News Authors: Tags: featured motivation self improvement success writing tips #success #doyourbest Source Type: blogs
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