Scientists Test Deep Brain Stimulation As Potential Anorexia Therapy

A small study in 16 people with severe anorexia has found that implanting stimulation electrodes into the brains of patients could ease their anxiety and help them gain weight. Researchers found that in extreme cases of the eating disorder, the technique - known as deep brain stimulation (DBS) - swiftly helped many of those studied reduce symptoms of either anxiety or depression, and improved their quality of life. A few months later, the improved psychological symptoms began to lead to changes in weight, the researchers said, with the average body mass index (BMI) of the group increasing to 17.3 – a rise of 3.5 points – over the course of the study. Anorexia is a serious eating disorder that affects around 0.5 percent of people worldwide, the majority of them teenage girls. Patients have persistent concerns about their weight, shape and size, and starve themselves to maintain a low weight. Chronic anorexia can be fatal, and in many cases causes severe health problems including weak bones and muscles, sexual problems, infertility, heart problems and seizures. The scientists who led this study, published in The Lancet Psychiatry journal on Friday, said their results suggest deep brain stimulation - which involves implanting electrodes to stimulate brain areas that control dysfunctional behaviors - might alter the brain circuits that drive anorexia. DBS is already used to target brain circuits involved in Parkinson’s disease and tremors - and been shown to be ...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

Related Links:

In conclusion, the evidence from current research supports the use of medical cannabis in the treatment of chronic pain in adults. Careful follow-up and monitoring of patients using cannabis/cannabinoids are mandatory. PMID: 30542280 [PubMed]
Source: Pain Physician - Category: Anesthesiology Authors: Tags: Front Pharmacol Source Type: research
Publication date: Available online 14 December 2018Source: Neurochemistry InternationalAuthor(s): Bruk Getachew, Antonei B. Csoka, Michael Aschner, Yousef TizabiAbstractManganese (Mn) and iron (Fe) are trace elements that are essential for proper growth and physiological functions as both play critical role in a variety of enzymatic reactions. At high concentrations, however, they can be toxic and cause neurodegenerative disorders, particularly Parkinson-like syndromes. Nicotine, on the other hand, has been shown to have neuroprotective effects against various endogenous or exogenous toxins that selectively damage the dopa...
Source: Neurochemistry International - Category: Neuroscience Source Type: research
Authors: Bondeelle L, Bergeron A Abstract INTRODUCTION: Progress in allogeneic hematopoietic stem cell transplantation (HSCT) procedures have been associated with improved survival in HSCT recipients. However, they have also brought to light organ-specific complications, especially pulmonary complications. In this setting, pulmonary complications are consistently associated with poor outcomes, and improved management of these complications is required. Areas covered: We review the multiple infectious and noninfectious lung complications that occur both early and late after allogeneic HSCT. This includes the descrip...
Source: Expert Review of Respiratory Medicine - Category: Respiratory Medicine Tags: Expert Rev Respir Med Source Type: research
Authors: Becker K, Schmidtke A, Glasow N Abstract Possibilities for Suicide Prevention Through Architecture in Child and Adolescent Psychiatry Abstract. In Germany, departments of Child and Adolescent Psychiatry are responsible for the treatment of young people with acute suicidal tendencies. Therefore, it is important to consider means of preventing suicide already during the construction and business operations of these institutions. Approaches to structural suicide prevention can be divided into restrictive and atmospheric-therapeutic measures. The latter includes ways to create an antisuicidal environment and t...
Source: Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie - Category: Child Development Tags: Z Kinder Jugendpsychiatr Psychother Source Type: research
In this study, we evaluated the potential oncolytic properties of other members of the Poxviridae family. Numerous tumor cell lines were infected with ten non-vaccinia poxviruses to identify which virus displayed the most potential as an oncolytic agent. Cell viability indicated that tumor cell lines were differentially susceptible to each virus. Raccoonpox virus was the most potent of the tested poxviruses and was highly effective in controlling cell growth in all tumor cell lines. To investigate further the oncolytic capacity of the Raccoonpox virus, we have generated a thymidine kinase (TK)-deleted recombinant Raccoonpo...
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
Authors: Kahl M, Wagner G, de la Cruz F, Köhler S, Schultz CC Abstract Resilience is defined as the psychological resistance which enables the processing of stress and adverse life events and thus constitutes a key factor for the genesis of psychiatric illness. However, little is known about the morphological correlates of resilience in the human brain. Hence, the aim of this study is to examine the neuroanatomical expression of resilience in healthy individuals. 151 healthy subjects were recruited and had to complete a resilience-specific questionnaire (RS-11). All of them underwent a high-resolution T1-weigh...
Source: European Archives of Psychiatry and Clinical Neuroscience - Category: Psychiatry Tags: Eur Arch Psychiatry Clin Neurosci Source Type: research
Authors: Goerigk S, Hilbert S, Jobst A, Falkai P, Bühner M, Stachl C, Bischl B, Coors S, Ehring T, Padberg F, Sarubin N Abstract The intentional distortion of test results presents a fundamental problem to self-report-based psychiatric assessment, such as screening for depressive symptoms. The first objective of the study was to clarify whether depressed patients like healthy controls possess both the cognitive ability and motivation to deliberately influence results of commonly used screening measures. The second objective was the construction of a method derived directly from within the test takers' response...
Source: European Archives of Psychiatry and Clinical Neuroscience - Category: Psychiatry Tags: Eur Arch Psychiatry Clin Neurosci Source Type: research
CONCLUSION: Utility values of EQ-5D-5L health states differ among Asian populations, suggesting that each health system should establish and use its own value set. PMID: 30523723 [PubMed - as supplied by publisher]
Source: Expert Review of Pharmacoeconomics and Outcomes Research - Category: Health Management Tags: Expert Rev Pharmacoecon Outcomes Res Source Type: research
CONCLUSION: The occurrence of CC hypoplasia on routine MRI scans could represent a "red flag" for suspicion of autism. PMID: 30546152 [PubMed - as supplied by publisher]
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - Category: Biomedical Science Tags: Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub Source Type: research
Patients do an IVF treatment with lots of hope and expectations .This is especially true when IVF doctors promise them the moon , and are extremely optimistic when they want them to sign up for treatment.However, when the cycle fails, their hopes come crashing down.Not only are they depressed and frustrated, they lose confidence in doctors - especially when the doctor abandons them , and refuses to answer their calls or provide them any information as to why the cycle failed, and what they can do differently next time.Patients feel cheated and will not trust any other IVF doctor.This is why a shared risk option can be so v...
Source: Dr.Malpani's Blog - Category: Reproduction Medicine Source Type: blogs
More News: Anorexia | Anxiety | Brain | Cardiology | Cerebellum | Deep Brain Stimulation | Depression | Eating Disorders & Weight Management | Girls | Heart | Infertility | Neurology | Parkinson's Disease | PET Scan | Psychiatry | Psychology | Reproduction Medicine | Study | Websites | Women