Local prothrombotic state in portal venous system in cirrhosis

Introduction: Cirrhosis is characterized by both bleeding and thrombotic complications due to underlying procoagulative haemostatic imbalance. Among thrombotic-events, portal-vein thrombosis (PVT) is the most common with annual incidence ranging between 4.6% and 12.8%. Demonstrated associated risk-factors are severity of portal-hypertension and slowed portal-flow. However, data regarding haemostasis in the portal venous-system of cirrhotics are lacking.
Source: Digestive and Liver Disease - Category: Gastroenterology Authors: Tags: OC-30 Source Type: research