Tyrosine assisted size controlled synthesis of silver nanoparticles and their catalytic, in-vitro cytotoxicity evaluation

Publication date: Available online 23 February 2017 Source:Environmental Toxicology and Pharmacology Author(s): Sireesh babu Maddinedi, Badal Kumar Mandal, Kiran Kumar Anna A simple, green approach for the size controllable preparation of silver nanoparticles (SNPs) using tyrosine as reducing and capping agent is shown here. The size of SNPs is controlled by varying the pH of tyrosine solution. The as synthesized SNPs are characterized by using XRD, UV-Vis, DLS, TEM and SAED. Zeta potential measurements revealed the stability of tyrosine capped silver nanocolloids. Furthermore, catalytic activity studies concluded that the smaller SNPs acts as good catalyst and the catalytic activity depends on size of the nanoparticles. Further, the in-vitro cytotoxicity experiments concluded that the cytotoxicity of the prepared SNPs towards mouse fibroblast (3T3) cell lines is size and dose dependent. Additionally, the present approach is substitute to the traditional methods that are being used now a days for size controlled synthesis of SNPs. Graphical abstract
Source: Environmental Toxicology and Pharmacology - Category: Environmental Health Source Type: research

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