DNA Virus Reactivation after Allogeneic Hematopoietic Stem Cell Transplantation (allo-HSCT)

Background: Allo-HSCT is curative for a variety of malignant and nonmalignant diseases. Unfortunately, immunosuppression after allo-HSCT is associated with reactivation of latent DNA viruses such as Herpes simplex, cytomegalovirus (CMV), Epstein-Barr virus (EBV) and adenovirus (Adv). Reactivation of these viruses increases the risks of complications after allo-HSCT.

Source: Biology of Blood and Marrow Transplantation - February 22, 2017 Category: Hematology Authors: Maia Tavadze, Melissa Baker, Michele Donato, Pashna N. Munshi, Andrew L. Pecora, Alan P. Skarbnik, David H. Vesole, Scott D. Rowley Source Type: research