A novel protein characterization based on Pseudo Amino Acids composition and Star-like graph topological indices.

A novel protein characterization based on Pseudo Amino Acids composition and Star-like graph topological indices.
Comb Chem High Throughput Screen. 2017 Feb 17;:
Authors: He P, Tao H, Ma T, Dai Q, Yao Y
Abstract
In the work, a new description of proteins based on five topological indices of star-like graph representation and the occurrence frequency of 20 amino acids was proposed to compare the similarities of proteins. A phylogenetic tree of eight ND6 proteins was constructed to demonstrate the effectiveness and rationality of our approach. Analogously, we applied this method to RNA polymerase proteins of some subtypes of influenza virus to infer their phylogenetic relationship. The results showed that the phylogenetic relationship among RNA polymerase of influenza virus is closely related to distributions of species virus host and geographical distribution.
PMID: 28215145 [PubMed - as supplied by publisher]

Source: Combinatorial Chemistry and High Throughput Screening - February 16, 2017 Category: Chemistry Authors: He P, Tao H, Ma T, Dai Q, Yao Y Tags: Comb Chem High Throughput Screen Source Type: research