Bone: miR-106b promotes osteoporosis in mice

Nature Reviews Rheumatology 13, 130 (2017). doi:10.1038/nrrheum.2017.11 Author: Joanna Collison The microRNA miR-106b contributes to osteoporosis by negatively regulating osteoblast differentiation and bone formation via the bone morphogenic protein 2 (BMP2) signalling pathway, according to new research. In vitro, miR-106b negatively regulated osteogenic differentiation of mesenchymal stem cells. Mice with glucocorticoid-induced osteoporosis (GIOP) expressed
Source: Nature Reviews Rheumatology - Category: Rheumatology Authors: Tags: Research Highlight Source Type: research