Peptide reverses cardiac fibrosis in a preclinical model of congestive heart failure

(Medical University of South Carolina) Cardiac fibrosis, an abnormal thickening of the heart wall leading to congestive heart failure, was not only halted but also reversed by a caveolin-1 surrogate peptide (CSD) in a preclinical model, report researchers at the Medical University of South Carolina in an article published online on Jan. 23, 2017 by Laboratory Investigation. CSD was able to decrease the fibrotic ventricular wall thickness and improve heart function, all with apparently no toxicity and minimal off-target effects.
Source: EurekAlert! - Social and Behavioral Science - Category: Global & Universal Source Type: news