Lymphadenectomy in Colorectal Cancer: Therapeutic Role and How Many Nodes Are Needed for Appropriate Staging?

AbstractSurgical resection with adequate lymphadenectomy is the treatment of choice for accurate diagnosis and proper treatment in colorectal cancer. Lymph node (LN) staging is an important prognostic factor in colorectal cancer and remains to be the most main criteria to select patients for adjuvant treatment. In colorectal cancer, a focus of treatment has been to collect as many LNs as possible to improve staging and increase survival. However, the scientific evidence for a minimum LN harvest remains controversial and the use of international cut-off values should be considered again. In practice, a thorough pursuit of a set high number of LNs may not be appropriate, but the best practice should be to collect as many LNs as possible.
Source: Current Colorectal Cancer Reports - Category: Cancer & Oncology Source Type: research