Teen: 'I want to do more stuff'

Spencer Kolman, 15, is the only US patient to undergo a heart/lung transplant in 2016.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news

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Abstract Exosomes are extracellular vesicles that express self-antigens (SAgs) and donor human leukocyte antigens. Tissue-specific exosomes can be detected in the circulation following lung, heart, kidney and islet cell transplantations. We collected serum samples from patients who had undergone lung (n=30), heart (n=8), or kidney (n=15) transplantations to isolate circulating exosomes. Exosome purity was analyzed by Western blot, using CD9 exosome-specific markers. Tissue-associated lung SAgs, collagen V (Col-V) and K-alpha 1 tubulin (Kα1T), heart SAgs, myosin and vimentin, and kidney SAgs, fibronectin and ...
Source: Human Immunology - Category: Allergy & Immunology Authors: Tags: Hum Immunol Source Type: research
In the current issue of the Journal of Heart and Lung Transplantation Farber and colleagues analyzed the REVEAL registry in order to investigate the impact of oxygen supplementation therapy in a large cohort of PAH patients1.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: Editorial Source Type: research
The allocation of donor hearts evolves in response to the changing landscape of advanced heart failure therapies and expanded understanding of donor/recipient matching. The novel, heart allocation algorithm is a natural response to the success of mechanical circulatory support (MCS) and further aligns severity of illness with urgency. In the novel, 6-status system, candidates supported with veno-arterial, extracorporeal membrane oxygenation devices (ECMO) and biventricular, extracorporeal ventricular assist devices (VAD) receive Status 1 urgency, while Status 2 urgency comprises candidates with univentricular extracorporea...
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: Editorial Source Type: research
Conclusion18F-FDG PET/CT and radiolabeled leucocyte scintigraphy single-photon emission computed tomography carry high performance in the diagnostic of LVAD infections.18F-FDG PET/CT shows significantly higher sensitivity and could be proposed as first-line nuclear medicine procedure.
Source: Journal of Nuclear Cardiology - Category: Nuclear Medicine Source Type: research
Conclusions Our analysis does not confirm previously reported associations between traffic-related air pollution exposure and the risk of transplant failure.
Source: Journal of Transport and Health - Category: Occupational Health Source Type: research
Community acquired respiratory virus (CARV) infections have been associated with significant acute morbidity and occasional mortality in lung transplant (LTX) recipients. Moreover, there is accumulating evidence that CARV infections may be associated with the development of chronic lung allograft dysfunction (CLAD) (1) for which bronchiolitis obliterans syndrome (BOS) is the most common phenotype although a restrictive phenotype is increasingly recognised (2, 3). CLAD, remains the most important complication limiting the long-term success of lung transplantation and occurs in 50% of recipients within 5 years (4).
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: Original Clinical Science Source Type: research
Abstract To paraphrase the lyrics of a song by Matchbox Twenty ("It's 3AM, I must be lonely"), it's 3 AM, I must be on a Lear jet. We're heading out to get a pair of lungs for a transplant. It's pitch black out tonight, and there's small rain falling. At least it's not ice or snow, which we've heard is falling to the north of us. I am glad that we'll be heading south on this run. These organ procurement runs tend to violate one of the basic safety rules of flying, which is to avoid, whenever possible, being required to fly. The edgy flights tend to stick in one's mind, of course. I've flown, literally, i...
Source: The Heart Surgery Forum - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Heart Surg Forum Source Type: research
Abstract PURPOSE OF REVIEW: The current review highlights the most relevant articles on lung infections following hematopoietic stem cell transplantation (HCT) published over the last year. Between 30 and 50% of HCT recipients will develop pulmonary infiltrates. These pulmonary complications may be infectious (caused by virus, bacteria, fungi, or protozoa) or noninfectious (e.g., fluid overload, heart failure, transfusion reactions like transfusion associated lung injury and transfusion-associated circulatory overload, drug reactions, engraftment syndrome, idiopathic pneumonia syndrome, diffuse alveolar hemorrhage...
Source: Current Opinion in Organ Transplantation - Category: Transplant Surgery Authors: Tags: Curr Opin Organ Transplant Source Type: research
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Authors: Paraskeva MA, Levin KC, Westall GP, Snell GI Abstract Lung transplantation in Australia is 32 years old in 2018. From its early infancy in 1986, it continues to evolve and is internationally recognised as demonstrating world's best practices in organ donation, utilisation and transplantation procedures. Over the past decade, transplant numbers have increased substantially due to innovations in donor procurement, such as donation after circulatory death, the use of ex vivo lung perfusion, extended criteria and organ utilisation, with more than 200 lung transplants undertaken in Australia annually. Parallel ...
Source: Medical Journal of Australia - Category: General Medicine Tags: Med J Aust Source Type: research
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