Regret and fear in prostate cancer: The relationship between treatment appraisals and fear of recurrence in prostate cancer survivors

ConclusionThese findings suggest that FOR may be mitigated by providing survivors with more information regarding treatment choices and the treatment itself so that men can make well‐informed decisions and experience less future regret.Sensitivity analysis for variables predicting FOR among prostate cancer survivors is not suspected of having a recurrence.
Source: Psycho-Oncology - Category: Cancer & Oncology Authors: Tags: PAPER Source Type: research

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In this study, a sensitive electrochemical aptasensor for detecting PSA based on coral-like poly-aniline (PANI)/gold nano-particles (AuNPs) and the peptides was constructed. Coral-like PANI and AuNPs with the diameter of 50-80 nm, as the substrate materials, were directly deposited on glass carbon electrode (GCE) by electrodeposited method. Then, the peptides, as the antifouling materials, were anchored on the modified-electrode, which not only can form antifouling surface to reduce nonspecific adsorption, but also can be as a medium between the modified-electrode and PSA aptamer. Finally, the PSA aptamer was immobi...
Source: Sensors and Actuators B: Chemical - Category: Chemistry Source Type: research
Publication date: Available online 20 May 2019Source: Respiratory Medicine Case ReportsAuthor(s): Yukihisa Hatakeyama, Sho Yoshimura, Taira Ninomaru, Shodai Fujimoto, Rei Takamiya, Kayoko Okamura, Nobuya Sano, Hisashi OhnishiAbstractA 78-year-old Japanese man who had undergone total prostatectomy for prostate cancer (pT3cN1M0, Gleason score 3 + 3) 20 years previously was referred to the Respiratory Medicine Department of our institution because of a 1-week history of chest pain and cough. Computed tomography showed multiple small nodules and mediastinal lymph node enlargement. Bronchoscopy revealed multiple soft ...
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
Condition:   Prostate Cancer Intervention:   Device: mpMRI Sponsor:   Institut Paoli-Calmettes Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: Available online 21 May 2019Source: Molecular and Cellular EndocrinologyAuthor(s): John J. Flanagan, Taavi K. NeklesaAbstractNuclear receptors comprise a class of intracellular transcription factors whose major role is to act as sensors of various stimuli and to convert the external signal into a transcriptional output. Nuclear receptors (NRs) achieve this by possessing a ligand binding domain, which can bind cell permeable agonists, a DNA-binding domain, which binds the upstream sequences of target genes, and a regulatory domain that recruits the transcriptional machinery. The ligand binding alters the a...
Source: Molecular and Cellular Endocrinology - Category: Endocrinology Source Type: research
Authors: Elkady AI Abstract Prostate cancer is still at the forefront causes of cancer-related morbidity and mortality in men throughout the globe. The disease is initiated and fostered by a subset of cancer stem cells (CSCs). Costus speciosus is an oriental herb used in traditional medicine and is a source of bioactive compounds with known pharmacological activities. The present study aims to evaluate the anticancer property of varied extracts isolated from C. speciosus against the human prostate cancer PC-3 cells. Extracts derived from C. speciosus were analyzed by chromatography-mass spectrometry and their effec...
Source: American Journal of Translational Research - Category: Research Tags: Am J Transl Res Source Type: research
ConclusionBoth [18F]FACBC and [11C]Met showed uptake in HCC through the use of a clinically relevant animal model of woodchuck HCC. The uptake and retention of [18F]FACBC and [11C]Met depend on their metabolism and also rely on the distribution of their principal amino acid transporters.
Source: EJNMMI Research - Category: Radiology Source Type: research
Conclusion BSI is a useful asset in stratification of patients with metastatic bone disease. It may also have a place in prediction of biochemical response.
Source: Nuclear Medicine Communications - Category: Nuclear Medicine Tags: ORIGINAL ARTICLES Source Type: research
Forced diuresis may improve readability of 2-(3-(1-carboxy-5-[(6-[18F]fluoro-pyridine-3-carbonyl)-amino]-pentyl)-ureido)-pentanedioic acid (18F-DCFPyL) PET/computed tomography (CT) by reducing focal ureteral activity. A total of 40 patients received furosemide simultaneously with 18F-DCFPyL (cohort 1) and 40 patients received furosemide 85 min after 18F-DCFPyL administration (cohort 2). The frequency of occurrence of activity depositions in ureters and halo artefacts near the kidneys and bladder was measured, as well as intensity of 18F-DCFPyL uptake in kidneys and bladder. At 120 min after injection of 18F-D...
Source: Nuclear Medicine Communications - Category: Nuclear Medicine Tags: TECHNICAL NOTE Source Type: research
Condition:   Prostate Cancer Intervention:   Diagnostic Test: Blood test: ClarityDX Prostate Sponsors:   Nanostics;   Alberta Prostate Cancer Research Initiative, APCaRI;   DynaLIFE Medical Laboratories;   Prostate Cencer Centre, Calgary;   Northern Alberta Urology Centre;   Alberta Cancer Foundation;   Alberta Innovates Health Solutions;   Motorcycle Ride for Dad;   Univers ity Hospital Foundation - The Kaye Fund Competition Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
(American Institute of Physics) Results reported in Biomicrofluidics promise a new way to detect prostate cancer through a simple device, which forces cell samples through channels less than 10 microns wide. When prostate cancer cells are forced through, the metastatic cells exhibit 'blebbing,' and the experiments show that highly metastatic prostate cancer cells are more likely to exhibit blebbing than normal cells or even less-metastatic cells are. The new device could be used to test large numbers of samples.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
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