Certain Thyroid-Related Diseases May Vary by Race
Study looked at Graves', Hashimoto's thyroiditis among U.S. military personnel Source: HealthDay Related MedlinePlus Pages: African American Health, Asian American Health, Thyroid Diseases
Conclusions: Overall, co-aggregation was more pronounced in monozygotic than in dizygotic twins, suggesting that disease overlap is largely attributable to genetic factors. Co-aggregation was common, and twins faced up to a ten-fold risk of developing diseases not present in their co-twin. Our results validate and refine previous heritability estimates based on smaller twin cohorts. PMID: 32229696 [PubMed - in process]
CONCLUSIONS: Our data describe a novel murine model of autoimmune thyroiditis which does not require the use of adjuvants to break down tolerance and that will allow investigators to test the effects of hTG variants in the pathoetiology of Hashimoto's thyroiditis (HT). PMID: 32228171 [PubMed - as supplied by publisher]
Background: Clinical and ultrasonic risk factors for lateral lymph node metastasis (LLNM) in papillary thyroid microcarcinoma (PTMC) are not well-defined. Herein, a systematic review and meta-analysis was conducted to investigate clinicopathologic and ultrasonic risk features for LLNM in PTMC.Methods: A systematic search of electronic databases (PubMed, Embase, Cochrane Library, and Web of Science) for studies published until April 2019 was performed. Case–control studies and randomized controlled trials that studied clinical and ultrasonic risk factors of LLNM in PTMC were included.Results: Fourteen studies (all ret...
CONCLUSIONS: Our findings suggest that the effect of miR-326 on the IL-23/IL-23R/Th17 cell axis in HT patients might be partially due to the targeting of ADAM17. PMID: 32204685 [PubMed - as supplied by publisher]
CORRIGENDUM FOR "A Case of Hashimoto's Thyroiditis with Multiple Drug Resistance and High Expression of Efflux Transporters". J Clin Endocrinol Metab. 2020 Apr 01;105(4): Authors: PMID: 32170861 [PubMed - as supplied by publisher]
Publication date: Available online 12 March 2020Source: Journal of Clinical &Translational EndocrinologyAuthor(s): Samir Naeim Assaad, Marwa Ahmed Meheissen, Eman Tayae Elsayed, Saher N. Alnakhal, Tarek M. Salem
Publication date: Available online 10 March 2020Source: Meta GeneAuthor(s): MahmoudAli Kaykhaei, Hosein Moghadam, Soroosh Dabiri, Saeedeh Salimi, Danial Jahantigh, Dor Mohammad Kordi Tamandani, Ava Rasouli, Mehrnaz Narooie-Nejad
Thyroid,Volume 30, Issue 3, Page 432-442, March 2020.
Primary lymphoma of the thyroid is an uncommon malignancy, whereas papillary thyroid carcinoma is the most common thyroid malignancy. Both have an association with Hashimoto's thyroiditis. We discuss a case of an 83 year old male who presented with a large neck swelling, which subsequently proved to be a primary thyroid lymphoma (extra-nodal marginal zone) with concurrent papillary thyroid carcinoma. These tumours manifested on a background of Hashimoto's thyroiditis. To date there have only been 13 other cases of joint papillary thyroid carcinoma and thyroid lymphoma within the literature.
International Journal of Rheumatic Diseases, EarlyView.