Freezing Nitrogen Ethanol Composite May be a Viable Approach for Cryotherapy of Human Giant Cell Tumor of Bone.

CONCLUSIONS: These preliminary in vitro and clinical findings suggest that freezing nitrogen ethanol composite may be an effective cryogen showing ex vivo and in vivo tumor cryoablation comparable to liquid nitrogen. The semisolid phase and proper thermal conduction might avoid some of the disadvantages of liquid nitrogen in cryotherapy, but a larger clinical study is needed to confirm these findings.
LEVEL OF EVIDENCE: Level IV, therapeutic study.
PMID: 28197783 [PubMed - as supplied by publisher]

Source: Clinical Orthopaedics and Related Research - February 13, 2017 Category: Orthopaedics Authors: Wu PK, Chen CF, Wang JY, Chen PC, Chang MC, Hung SC, Chen WM Tags: Clin Orthop Relat Res Source Type: research