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Postmenopausal hormone therapy exceeding ten years may protect from dementia

Postmenopausal estrogen-based hormone therapy lasting longer than ten years was associated with a decreased risk of Alzheimer's disease in a large study. The study explored the association between postmenopausal hormone replacement therapy, Alzheimer's disease, dementia and cognition in two nation-wide case-control studies and two longitudinal cohort studies. The largest study comprised approximately 230,000 Finnish women and the follow-up time in different studies was up to 20 years.
Source: ScienceDaily Headlines - Category: Science Source Type: news

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I did and much to my surprise my mother answered without hesitation - Saint Monica's.I had this conversation with my mother in 2010. To put this in context, Dotty first attended Saint Monica's in 1922. At the time of the conversation she was 93 years old; and, in the moderate to severe stage of Alzheimer's.To learn more about this episode go to this article -I Had to Remind Myself - My Mom Was Deeply Forgetful- and look for the story about half way down the page.Solutions to challenges facing caregiversByBob DeMarcoAlzheimer's Reading RoomI'm writing this article because I have been asked several times recently -How do you...
Source: Alzheimer's Reading Room, The - Category: Neurology Tags: alzheimers awareness caregiving deeply forgetful don't be afraid lesson learned living with dementia love dementia memory Source Type: blogs
When the brain struggles to make sense of the world it may be less able to perform other important tasks.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Ears and Hearing Eyes and Eyesight Memory Alzheimer's Disease Brain Elderly Dementia Hearing Aids Source Type: news
(Florida Atlantic University) With disease-modifying treatment trials for Alzheimer's disease (AD) currently unsuccessful and only medications to treat symptoms available, what now? A leading neuroscientist has developed the " Dementia Prevention Initiative, " which abandons generalized ways to research and treat AD. His secret weapon: a novel " N-of-1 design " that tailors medicine down to a single patient. Instead of conducting a conventional trial of 100 people all getting the same treatment, he has switched it around and is conducting 100 single personalized trials.
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news
Publication date: 2017 Source:Handbook of Clinical Neurology, Volume 144 Author(s): Fernando Pagan, Yasar Torres-Yaghi, Marcelle Altshuler Huntington disease (HD) is an autosomal-dominant disorder resulting from CAG triplet repeats, which leads to an expanded polyglutamine sequence in the HTT (Huntingtin) protein. Accumulation of the Huntingtin protein ultimately leads to neurodegeneration and negative effects in multiple clinical domains, including motor function, cognition, and behavior. HD is a disorder governed by genetics, and the ability to quantify the CAG triplet repeats can provide important insight regarding cli...
Source: Handbook of Clinical Neurology - Category: Neurology Source Type: research
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
At present there is no therapy for Alzheimer ’s Disease which completely stops the progressive dementia effecting late onset Alzheimer’s Disease (AD) patients. It is felt that the main reason for this failure is that AD appears to be a disease caused by four major pathological processes. To date, efforts to develop treatments have addresse d only one or another of these four etiologies. However, even a partially effective therapy against one cause allows the others, untreated, to continue their inexorable destruction of the neurons of the brain.
Source: Medical Hypotheses - Category: Biomedical Science Authors: Source Type: research
Dear Carol: My mom moved into the memory unit of an assisted living last year and she loves it. She’s very social so this environment is perfect for her. Now, my brother has suddenly decided that he wants Mom to come and stay with him for the winter since he lives in a warmer climate. He’s the man so he has the Power Of Attorney. Mom doesn’t want to leave her comfortable little apartment, but she’s said if he really wants her there for a time, she should do it. My fear is that the move could make her dementia worse. My brother says he just wants to spend more time with Mom, but he's n...
Source: Minding Our Elders - Category: Geriatrics Authors: Source Type: blogs
Abstract In elderly patients, bullous pemphigoid (BP) is associated with several comorbidities; the strongest association occurs between BP and neurological diseases. Different types of dementia, Parkinson's disease, cerebrovascular disorders and epilepsy all have a significant association with BP, but patients with multiple sclerosis have the highest risk of BP. An existing neurological disorder appears to increase the risk for subsequent BP, but an increased risk for developing some neurological diseases has also been reported following BP diagnosis. BP seems to be associated with several psychiatric diseases such as sch...
Source: Experimental Dermatology - Category: Dermatology Authors: Tags: REVIEW Source Type: research
Authors: Khachaturian AS, Hoffman DP, Frank L, Petersen R, Khachaturian ZS PMID: 28935202 [PubMed - as supplied by publisher]
Source: The Journal of Alzheimers Association - Category: Psychiatry Tags: Alzheimers Dement Source Type: research
ConclusionFuture research in the form of large longitudinal observational study is needed to validate our findings, particularly regarding the potential association of stearic acid with cortical A β.
Source: The Journal of Nutrition, Health and Aging - Category: Nutrition Source Type: research
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