FDA Expands Approval of SPIRIVA(R) RESPIMAT(R) (tiotropium bromide) Inhalation Spray for Maintenance Treatment of Asthma in Children

RIDGEFIELD, Conn., Feb. 16, 2017 -- (Healthcare Sales &Marketing Network) -- Boehringer Ingelheim Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration (FDA) approved SPIRIVA RESPIMAT for the long-term, once-daily maintenance t... Biopharmaceuticals, FDA Boehringer Ingelheim, SPIRIVA, RESPIMAT, tiotropium bromide, Asthma
Source: HSMN NewsFeed - Category: Pharmaceuticals Source Type: news

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Publication date: Available online 22 June 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Erika J. Yoo, Nora L. Lee, Kelly P. Huang, Lara T. Kose, Deval Desai, Lauren A. Plante, Edward S. Schulman
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
ConclusionsThe effectiveness of LTRAs was not different from that of low-dose ICSs regarding the risk of asthma exacerbation in elderly patients with asthma in real-world settings. Given the practical benefits gained from convenient administration, LTRAs can be considered a reasonable alternative first-line therapy for elderly patients with mild asthma.
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Publication date: 22 June 2019Source: New Scientist, Volume 242, Issue 3235Author(s): Chelsea Whyte
Source: New Scientist - Category: Science Source Type: research
Conclusion: An electronic alert incorporated into the ED workflow to populate a discharge order set is effective to initiate asthma controller medication for poorly controlled pediatric patients. Additional data describing reasons for not prescribing ICS can further refine recommendations for ICS prescriptions, and provide a comprehensive strategy to support clinical decision for pediatric asthma control in acute care settings. PMID: 31226000 [PubMed - as supplied by publisher]
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
Conclusions: Stimulating positive illness perceptions and medication beliefs might improve adherence, which in turn might lead to improved disease control and better quality of life. PMID: 31225980 [PubMed - as supplied by publisher]
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
Authors: Giangioppo S, Bijelic V, Barrowman N, Radhakrishnan D Abstract OBJECTIVES: Resource limitations and low rates of follow-up with primary care providers currently limit the impact of emergency department (ED)-based preventative strategies for children with asthma. A mechanism to recognize the children at highest risk of future hospitalization is needed to target comprehensive preventative interventions at discharge. The primary objective of this study was to determine if frequency of ED visits predicts future asthma hospitalization in children. METHODS: Children aged 2-16.99 years with asthma ED visits b...
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
Authors: Čepelak I, Dodig S, Pavić I Abstract There is an increasing number of experimental, genetic and clinical evidence of atopic dermatitis expression as a pre-condition for later development of other atopic diseases such as asthma, food allergy and allergic rhinitis. Atopic dermatitis is a heterogeneous, recurrent childhood disease, also present in the adult age. It is increasingly attributed to systemic features and is characterized by immunological and skin barrier integrity and function dysregulation. To maintain the protective function of the skin barrier, in particular the maintenance of pH, hydration a...
Source: Biochemia Medica - Category: Biochemistry Tags: Biochem Med (Zagreb) Source Type: research
This study tries to investigate the role of lncRNA TUG1 for the ASMCs and focus on the deepgoing mechanism in the proliferation and migration. In the asthma rat model, TUG1 expression level was increased comparing with control. In the cellular assay with gain and loss of functions, lncRNA TUG1 promoted the ASMCs proliferation and migration, and reduces apoptosis. In the mechanical investigation, results unveiled that miR-590-5p acted as the target of TUG1, while FGF1 was targeted by miR-590-5p. Overall, this study reveals the vital regulation of TUG1/miR-590-5p/FGF1 axis for the proliferation and migration of ASMCs. PM...
Source: American Journal of Translational Research - Category: Research Tags: Am J Transl Res Source Type: research
Publication date: Available online 20 June 2019Source: The LancetAuthor(s): Guy G Brusselle, Fanny Wai-San Ko
Source: The Lancet - Category: General Medicine Source Type: research
Publication date: Available online 20 June 2019Source: The LancetAuthor(s): Kewu Huang, Ting Yang, Jianying Xu, Lan Yang, Jianping Zhao, Xiangyan Zhang, Chunxue Bai, Jian Kang, Pixin Ran, Huahao Shen, Fuqiang Wen, Yahong Chen, Tieying Sun, Guangliang Shan, Yingxiang Lin, Guodong Xu, Sinan Wu, Chaolong Wang, Ruiying Wang, Zhihong ShiSummaryBackgroundAsthma is a common chronic airway disease worldwide. Despite its large population size, China has had no comprehensive study of the national prevalence, risk factors, and management of asthma. We therefore aimed to estimate the national prevalence of asthma in a representative s...
Source: The Lancet - Category: General Medicine Source Type: research
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