Don't mistake it as a polyp!

CLINICAL PRESENTATION A middle-aged woman first presented with vague abdominal symptoms of bloatedness and change in bowel habits. Physical examination was otherwise unremarkable. A colonoscopic evaluation was performed, which demonstrated a possible appendiceal mass (figure 1). A CT scan of the abdomen and pelvis was performed, which confirmed the bulky appendix (figure 2). In view of the indeterminate nature of the lesion and inability to rule out an underlying neoplastic process, the patient was counselled for surgical resection of the appendix, with the possibility of a limited right hemicolectomy. Intraoperatively, the right ovary and fallopian tube were densely adherent to the caecal pole (figure 3). The appendix was not discernable even with open dissection, although a palpable mass was present in the caecum. As such, an ileo-caecectomy was performed. The specimen was cut open which revealed a bulky appendiceal prominence in the...
Source: Gut - Category: Gastroenterology Authors: Tags: GUT Snapshot Editor ' s quiz: GI snapshot Source Type: research

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Publication date: Available online 23 January 2020Source: Journal of Minimally Invasive GynecologyAuthor(s): Whitney Trotter Ross, Jordan M. Newell, Richard Zaino, Allen R. Kunselman, Gerald J. Harkins, Andrea S. BentonAbstractStudy ObjectiveTo evaluate the diagnosis of appendiceal endometriosis in coincidental appendectomy specimens using a standard versus modified histopathologic analysis.DesignProspective analysis of 300 consecutive patients undergoing coincidental appendectomy at time of a primary gynecologic procedure.SettingAcademic tertiary referral hospital in the Northeastern United States.PatientsWomen ages 22 to...
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
ConclusionWe reported a Tunisian case of Paneth cell colonic adenocarcinoma. The diagnosis is challenging in biopsies when only well-differentiated areas are sampled. Lysozyme immune-histochemical stain may be helpful when diagnosis difficulty arises. The beta-catenin pathway seems to be activated. More studies are needed for the etiology, pathogenesis, clinical course, prognosis and treatment of Paneth cell carcinoma.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
CONCLUSIONS: A policy ofroutine appendicectomy atthe time of pancreas transplant appears to be justified and safe. PMID: 31580234 [PubMed - as supplied by publisher]
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - Category: Transplant Surgery Authors: Tags: Exp Clin Transplant Source Type: research
AbstractThere are known short-term benefits in breastfed infants versus bottle-fed infants in terms of lower risks of infection and obesity in infancy and childhood, but the long-term effect on the risk of adult cancers is unclear. In a cohort of 1 in 4 UK women born in 1935 –1950 we report the incidence of adult cancers in relation to having been breastfed in infancy. In median year 2001 (interquartile range 2000–2003) 548,741 women without prior cancer reported whether they had been breastfed. There was 81% agreement between women’s report of having been breastf ed and information on breastfeeding recor...
Source: European Journal of Epidemiology - Category: Epidemiology Source Type: research
The newly published guideline of Japanese Gastroenterological Endoscopy Society (2017 appendix) suggests to undergo endoscopic resection of colorectal polyps under anticoagulant therapy without stopping warfarin if PT-INR is under its therapeutic range, and in case of direct oral anticoagulants (DOACs), with stopping the drug only on the day of the treatment. However, the recommendation is not based on the established evidence. Thus, we aimed to evaluate the rate of bleeding and clarify its risk factors after endoscopic resection of colonic polyps performed according to the guideline in patients under anticoagulant therapy.
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: Monday abstract Source Type: research
ConclusionsPatients aged 55  years or over who have undergone appendicectomy should be offered colonoscopy to exclude coexistent caecal pathology.
Source: International Journal of Colorectal Disease - Category: Gastroenterology Source Type: research
ConclusionDespite the advancement in visualization of anatomy with CT scan and laparoscopic appendicectomy there is still a role for screening colonoscopy in patients greater than 50 years of age with appendicitis particularly if they have associated bowel symptoms or risk factors for CRC.
Source: Annals of Medicine and Surgery - Category: General Medicine Source Type: research
Conclusion This small exploratory study suggests that eFTR of appendiceal polyps is feasible and can offer a minimally invasive approach for radical resection of these lesions. However, more safety and long-term follow-up data are needed to evaluate this evolving technique. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text
Source: Endoscopy International Open - Category: Gastroenterology Authors: Tags: Case report Source Type: research
gün AS, Erdoğan N Abstract Appendiceal mucinous neoplasms constitute a diagnostic spectrum ranging from adenoma to mucinous adenocarcinoma. To date, many classification systems have been proposed to reflect the histomorphological diversity of neoplasms in this range and their clinical correspondence, and also to form a common terminology between the pathologist and clinicians. The aim of this review is to provide an updated perspective on the pathological features of appendiceal mucinous neoplasms. Using the 2016 Modified Delphi Consensus Protocol (Delphi) and the Eighth Edition of the American Joint Committ...
Source: The Turkish Journal of Gastroenterology - Category: Gastroenterology Authors: Tags: Turk J Gastroenterol Source Type: research
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog aka Tropical Travel Trouble 004 A medical student who has just returned from their elective in Nepal presents with 1 week of bloody diarrhoea. He has been in the lowlands and stayed with a family in the local village he was helping at. It started three days before he left and he decided to get home on the plane in the hope it would settle. He is now opening his bowels 10x a day with associated cramps, fevers and has started feeling dizzy. Questions: Q1. What is dyse...
Source: Life in the Fast Lane - Category: Emergency Medicine Authors: Tags: Clinical Cases Tropical Medicine amoebic dysentery bacillary dysentery e.histolytica entamoeba histolytica shigellosis Source Type: blogs
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