Role of TLR1, TLR2 and TLR6 in the modulation of intestinal inflammation and Candida albicans elimination

ConclusionIn contrast to TLR6, both TLR1 and TLR2 deficiencies increased intestinal inflammation, and the overgrowth ofC. albicans andE. coli populations in the colitis model, suggesting the involvement of TLR1 and TLR2 in epithelial homeostasis, and a role of TLR6 in increasing intestinal inflammation in response to pathogen-sensing.

http://link.springer.com/10.1186/s13099-017-0158-0

Source: Gut Pathogens - February 14, 2017 Category: Microbiology Source Type: research