Ubiquitous and influential

(University of W ü rzburg) Scientists at the University of W ü rzburg have generated new insights into the intricate molecular underpinnings of ubiquitin signaling. Their results may provide new avenues for cancer therapy.
Source: EurekAlert! - Medicine and Health - Category: Global & Universal Source Type: news

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ConclusionsNeither patient nor physician race was significantly associated with risk estimation or surgical recommendations. These findings do not provide an explanation for documented racial disparities in lung cancer therapy. Further investigation is needed to identify the mechanism underlying these disparities.Visual Abstract
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Professor Judi Fouladbakhsh speaks withCancer Network about evidence-based holistic approaches to cancer care.
Source: CancerNetwork - Category: Cancer & Oncology Authors: Source Type: news
Jakob von Frieling, Christine Fink, Jacob Hamm, Kenneth Klischies, Michael Forster, Thomas C. G. Bosch, Thomas Roeder, Philip Rosenstiel, Felix Sommer
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Publication date: Available online 20 September 2018Source: Results in PhysicsAuthor(s): Limin Dong, Dongyue Liu, Xuejiao Li, Kejia Wu, Wanqi ZhangAbstractBiomass carbon quantum dots (CQDs) were widely used in bioimaging and WO2.72 has great potential in cancer therapy. The biomass CQDs were prepared by mixed acid oxidation method with biomass materials such as pods, tobacco leaves and cysteine as carbon sources. Properties of biomass carbon quantum dots were characterized, including micromorphology, the functional group composition, photoluminescence properties and fluorescence labeling ability in HepG2 cells. And the cyt...
Source: Results in Physics - Category: Physics Source Type: research
Authors: Zhang D, Dong Y, Zhao Y, Zhou C, Qian Y, Hegde ML, Wang H, Han S Abstract The use of plant‑based compounds derived from traditional medicine to improve human diseases has been gaining momentum, due to their high bioavailability and moderate adverse effects. Sinomenine is one such biomonomer alkali compound derived from Sinomenium acutum and is known for its anti‑inflammatory and antitumor effects. However, the molecular mechanism(s) of its antitumor properties are not fully characterized. In the present study, we evaluated the radiosensitizing effects of the water‑soluble sinomenine, sinomenine hydro...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
Authors: Lopes-Souza P, Dionello CF, Sá-Caputo DDC, Moreira-Marconi E, Frederico EHFF, Marchon RM, Bergmann A, Furness T, Bernardo-Filho M Abstract The purpose of this systematic review was to investigate the effects of whole body vibration (WBV) exercise in the management of cancer therapy-related morbidities. The PubMED and PEDro databases were used to access publications published in English about the use of whole body vibration (WBV) exercises in cancer patients until February 22nd 2017. The studies included were classified according to the level of evidence (LE) by the National Health and Medical Resear...
Source: Drug Discoveries and Therapeutics - Category: Drugs & Pharmacology Tags: Drug Discov Ther Source Type: research
International Journal of Dermatology, EarlyView.
Source: International Journal of Dermatology - Category: Dermatology Authors: Source Type: research
Galectin-3 (Gal-3) is a promising target in cancer therapy with a high therapeutic potential due to its abundant localization within the tumor tissue and its involvement in tumor development and proliferation....
Source: Journal of Nanobiotechnology - Category: Nanotechnology Authors: Tags: Research Source Type: research
Publication date: 1 January 2019Source: Materials Science and Engineering: C, Volume 94Author(s): Lijun You, Xiaocui Liu, Zhexiang Fang, Qianhui Xu, Qiqing ZhangAbstractA new folic acid (FA)-conjugated poly (lactic-co-glycolicacid) (PLGA)-polyethylene glycol (PEG) nano-noisome was prepared. The noisome was employed as a drug delivery system to load curcumin (Cur) as a model drug and fluorescent probe for cervical cancer therapy and cell imaging. The Fe3O4@PLGA-PEG@FA noisomes were prepared through facile emulsion solvent evaporation and conjugation chemistry method, possessing the properties of high rapid magnetic separati...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
Authors: Mukherjee A, Waters AK, Babic I, Nurmemmedov E, Glassy MC, Kesari S, Yenugonda VM Abstract Antibody drug conjugates (ADC's) represent a promising and an efficient strategy for targeted cancer therapy. Comprised of a monoclonal antibody, a cytotoxic drug, and a linker, ADC's offer tumor selectively, reduced toxicity, and improved stability in systemic circulation. Recent approvals of two ADC's have led to a resurgence in ADC research, with more than 60 ADC's under various stages of clinical development. The therapeutic success of future ADCs is dependent on adherence to key requirements of their design and ...
Source: Human Antibodies - Category: Biochemistry Tags: Hum Antibodies Source Type: research
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