Chemical Constituents and Inhibition Xanthine Oxidase Activity of Avicennia marina Exudate
Conclusion: The identification results of component in the active by UV-vis spectrometer and FTIR thought to contain 5,7,3',4' tetrahidroxyflavone (Luteolin).
People withgout are not generally at an increased risk of suffering a fracture, new research has shown. A study funded by NIHR and led by researchers based atArthritis Research UK Primary Care Centre at Keele University has shown that neither the disease itself nor its associated treatments are likely to increase a person's risk of broken bones. A large-scale study An increased risk of fractures is often associated with chronic inflammatory conditions. The new research aimed to clarify whether this is the case for people with gout - a form of inflammatory arthritis. The researchers followed more than 30,000 people with...
Authors: Deschamps R, Stankoff B, Vignal C, Benoist JF, Wolf B, Gout O PMID: 29778138 [PubMed - in process]
Abstract In 2014, the Japanese Society of Hypertension (JSH) issued revised guidelines for hypertension management. To assess adherence to the guidelines, this retrospective study evaluated the real-world status of antihypertensive drug prescribing for Japanese patients with hypertension, classified by comorbidity: diabetes mellitus, dyslipidemia, gout/hyperuricemia and renal diseases. Data on 59,867 hypertensive patients who received their first prescription for antihypertensive therapy between April 2014 and March 2015, were obtained from a medical insurance claims database for hospitals participating in the Dia...
Publication date: Available online 19 May 2018 Source:Joint Bone Spine Author(s): Frédéric Lioté
Conclusions The main genetic cause of ADTKD in our Spanish cohort is the MUC1 pathogenic mutation c.(428)dupC. Renal survival may be worse in individuals with the MUC1 mutation than in those with UMOD mutations. Clinical presentation does not permit distinguishing between these variants. However, hyperuricemia and gout are more frequent in individuals with ADTKD-UMOD.
Comment on: Carotid-cavernous fistula: current concepts in aetiology, investigation and management, Published online: 18 May 2018; doi:10.1038/s41433-018-0112-5Comment on: Carotid-cavernous fistula: current concepts in aetiology, investigation and management
This article enhances the recognition and treatment of these diseases in the primary care setting. PMID: 29759121 [PubMed - in process]
This article discusses the major clinical risks associated with colchicine, NSAIDs and glucocorticoids and risk minimisation strategies for their safe and effective use in this patient population.
Authors: Sultan AA, Whittle R, Muller S, Roddy E, Mallen CD, Bucknall M, Helliwell T, Hider S, Paskins Z Abstract BACKGROUND: Previous studies that quantified the risk of fracture among patients with gout and assessed the potential effect of urate-lowering therapy have provided conflicting results. Our study aims to provide better estimates of risk by minimizing the effect of selection bias and confounding on the observed association. METHODS: We used data from the Clinical Practice Research Datalink, which records primary care consultations of patients from across the United Kingdom. We identified patients wit...
The history of osteoarthritis (OA) is important because it can help broaden our perspective on past and present controversies. The naming of OA, beginning with Heberden's nodes, is itself a fascinating story. According to Albert Hoffa, R. Llewellyn Jones and Archibald Edward Garrod, the name OA was introduced in the mid-19th century by surgeon Richard von Volkmann who distinguished it from rheumatoid arthritis and gout. Others preferred the terms 'chronical rheumatism', 'senile arthritis', 'hypertrophic arthritis' or 'arthritis deformans'.