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Chemical Constituents and Inhibition Xanthine Oxidase Activity of Avicennia marina Exudate

Conclusion: The identification results of component in the active by UV-vis spectrometer and FTIR thought to contain 5,7,3',4' tetrahidroxyflavone (Luteolin).
Source: Research Journal of Medicinal Plant - Category: Complementary Medicine Source Type: research

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PMID: 29470212 [PubMed - in process]
Source: The American Journal of Nursing - Category: Nursing Authors: Tags: Am J Nurs Source Type: research
Preliminary results from a clinical safety trial of the gout medication febuxostat (Uloric) indicate that, when compared with allopurinol, the standard gout treatment, febuxostat increases the risk of heart-related deaths.The Food and Drug Administration will provide additional information after the final trial results are submitted and analyzed.
Source: AJN - Category: Nursing Tags: Drug Watch Source Type: research
Purposes The aim of this study was to investigate the serum levels and clinical significance of interleukin 1β (IL-1β) and IL-6 in children with hyperuricemia (HUA). Methods We included 71 children with HUA and 71 children with no HUA as control subjects. Children with HUA were divided into groups I and II according to whether they had a history of acute gout-like attacks (including sudden monoarthritis of rapid onset with intense pain and swelling). Group I was examined twice (A, in the acute phase; B, in the remission phase). Serum IL-1β and IL-6 levels were measured by enzyme-linked immunosorbent ass...
Source: JCR: Journal of Clinical Rheumatology - Category: Rheumatology Tags: Original Articles Source Type: research
Conclusions Electronic medical records are promising tools for assessing QIs for gout. It was feasible to translate seven gout QIs into relevant EMR variables and there was sufficient EMR data to feasibly assess six of these QIs –Our findings lend evidence to support the utility of EMRs for ut QI assessment, with implications for helping improve management of this disease.
Source: JCR: Journal of Clinical Rheumatology - Category: Rheumatology Tags: Original Articles Source Type: research
A drug used for the treatment of gout has been found to improve heart functioning in a small number of people with heart failure, researchers reveal.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Heart Disease Source Type: news
Follow me on Twitter @RobShmerling Ever wonder what other people are wondering about? I know I do. So, here are the top 10 health searches in Google for 2017. And just so you don’t have to look each one up, I’ve provided a brief answer. You’re welcome. 1.  What causes hiccups? I was surprised this one made it to the top 10 list of health searches. Maybe this search is common because hiccups are as mysterious as they are universal. I’ve written about hiccups before, but let’s just say the cause in any individual person is rarely known or knowable. Then again, the reason hiccups stop is als...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health Source Type: blogs
Authors: Fornaciari A, Giuffra V, Armocida E, Caramella D, Rühli FJ, Galassi FM Abstract The article examines the truthfulness of historical accounts claiming that Renaissance Duke Federico of Montefeltro (1422-1482) suffered from gout. By direct paleopathological assessment of the skeletal remains and by the philological investigation of historical and documental sources, primarily a 1461 handwritten letter by the Duke himself to his personal physician, a description of the symptoms and Renaissance therapy is offered and a final diagnosis of gout is formulated. The Duke's handwritten letter offers a rare test...
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
Molecules, Vol. 23, Pages 466: Comparison of Inhibitory Capacities of 6-, 8- and 10-Gingerols/Shogaols on the Canonical NLRP3 Inflammasome-Mediated IL-1β Secretion Molecules doi: 10.3390/molecules23020466 Authors: Su-Chen Ho Yi-Huang Chang Endogenous noninfectious substances that mediate the nucleotide oligomerization domain (NOD)-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome activation and interleukin (IL)-1β secretion causes inappropriate sterile inflammation and is implicated in the pathogenesis of several chronic diseases, such as type 2 diabetes mellitus, gout, atherosclerosis...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
The primary efficacy outcome in trials of urate lowering therapy (ULT) for gout is serum urate (SU). The aim of this study was to examine the strength of the relationship between SU and patient-important outcomes to determine whether SU is an adequate surrogate endpoint for clinical trials.
Source: Seminars in Arthritis and Rheumatism - Category: Rheumatology Authors: Source Type: research
ConclusionIn asymptomatic individuals with chronic hyperuricemia, the presence of synovitis and double contour sign by US may represent a subclinical manifestation of monosodium urate crystals nucleation, capable of triggering inflammatory pathways (IL‐6 and IL‐8) and mechanisms of intercellular communication (miR‐155) similar to what is observed in gout.This article is protected by copyright. All rights reserved.
Source: Arthritis Care and Research - Category: Rheumatology Authors: Tags: Original Article Source Type: research
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