Combined genome-wide linkage and targeted association analysis of head circumference in autism spectrum disorder families

ConclusionsAlthough this region does not overlap with ASD linkage signals in these same samples, it has been associated with other psychiatric risk, including ADHD, developmental dyslexia, schizophrenia, specific language impairment, and juvenile bipolar disorder. The genome-wide significant linkage signal represents the first reported observation of a potential quantitative trait locus for HC in ASD and may be relevant in the context of complex multivariate risk likely leading to ASD.
Source: Journal of Neurodevelopmental Disorders - Category: Neurology Source Type: research