[Alzheimer's disease and epilepsy].

[Alzheimer's disease and epilepsy].
Nervenarzt. 2017 Feb 10;:
Authors: Haussmann R, Mayer T, Schrempf W, Donix M
Abstract
Data regarding the incidence and prevalence of epileptic seizures in Alzheimer's disease show great variability and are clinically underestimated due to their atypical symptomatology. Considering their considerable negative effects on cognition and activities of daily living, epileptic seizures need to be correctly treated. Hypotheses with respect to the pathogenetic mechanisms and associations between Alzheimer's disease and epilepsy are mostly derived from animal experiments. The causal connections are so far insufficiently understood. Data on risk factors are inconsistent due to methodological limitations in studies. Clinical data for these indications show good response to therapy with anticonvulsants and good tolerability in the case of new active substances. When treating epileptic seizures in this patient collective using anticonvulsants, potential adverse effects and possible drug interactions need to be closely monitored.
PMID: 28188402 [PubMed - as supplied by publisher]

Source: Der Nervenarzt - February 9, 2017 Category: Neurology Authors: Haussmann R, Mayer T, Schrempf W, Donix M Tags: Nervenarzt Source Type: research