Sex differences in the psychopharmacological treatment of depression.

Sex differences in the psychopharmacological treatment of depression. Dialogues Clin Neurosci. 2016 Dec;18(4):447-457 Authors: Sramek JJ, Murphy MF, Cutler NR Abstract Although a number of studies have observed that females respond better to serotonergic antidepressants than males and that postmenopausal females have a diminished response to antidepressants compared with younger females, there are also studies that conflict with both of these findings, making any generalizations regarding sex differences difficult to make. Sex variance in antidepressant efficacy and pharmacokinetics profiles have been attributed to sex-based physiological differences, behavioral differences, related disorders, and sex-specific conditions, including pregnancy and menopause. This paper will review the history and current research on sex effects of antidepressant treatment. PMID: 28179816 [PubMed - in process]
Source: Dialogues in Clinical Neuroscience - Category: Neuroscience Tags: Dialogues Clin Neurosci Source Type: research