The clinical and neurobehavioral course of Down syndrome and dementia with or without new-onset epilepsy

Discussion New-onset epilepsy seems to occur early in the course of dementia in DS patients. Patients generally respond to treatment. A great burden of neuropsychiatric symptoms is seen. Future studies need to explore the relationship between β-amyloid accumulation and epileptiform activity and attend to the care and needs of DS patients with dementia and seizures.
Source: Epilepsy and Behavior - Category: Neurology Source Type: research