Viruses, Vol. 9, Pages 29: A Review of the Strain Diversity and Pathogenesis of Chicken Astrovirus

Although a relatively recently emerged virus, identified only in 2004 as a separate species of avian astrovirus, chicken astrovirus (CAstV) has been associated with poor growth of broiler flocks, enteritis and diarrhea and is a candidate pathogen in cases of runting stunting syndrome. More recently CAstV has been implicated in cases of two other diseases of broilers as the sole etiological agent, namely severe kidney disease of young broilers with visceral gout and the “White Chicks” hatchery disease. Examination of the strains of CAstV associated with the two latter diseases reveals they are closely related genetically. This review will discuss the pathogenesis of CAstV in relation to strain diversity and the effects of vertical versus horizontal transmission , virus load, co-infections and age of bird at infection, all factors that may impact upon disease severity.
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research

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Source: Progress in Neurobiology - Category: Neuroscience Source Type: research
Foodborne viruses were recognized among the top-rated food safety priorities and have become a greater concern to the food industry over the past few years. Food safety experts agreed that control measures for viruses throughout the food chain are required. This manuscript provides a description of foodborne viruses (Rotavirus, Adenovirus, Norovirus, Astrovirus, Hepatitis A, Hepatitis E, and...
Source: African Journal of Microbiology Research - Category: Microbiology Source Type: research
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Conditions:   Gout;   Hyperuricemia Interventions:   Dietary Supplement: Probiotics;   Drug: uric-acid-lowering drug Sponsor:   The Affiliated Hospital of Inner Mongolia Medical University Recruiting
Source: - Category: Research Source Type: clinical trials
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Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
In this study, the virulence of a cytopathic porcine astrovirus (PAstV) strain (PAstV1-GX1) isolated from the PK-15 cell line was tested using seven-day-old nursing piglets. The results showed that PAstV1-GX1 infection could cause mild diarrhea, growth retardation, and damage of the villi of the small intestinal mucosa. However, all the above symptoms could be restored within 7 to 10days post inoculation (dpi). To evaluate the innate immunity response of PAstV in vivo, the alteration of inflammatory cytokine expression in piglets infected with PAstV1-GX1 was determined using quantitative real-time reverse transcription pol...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
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Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
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Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
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Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
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Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
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