Health-related quality of life after mechanical ventilation in the intensive care unit.

CONCLUSIONS: The EORTC QLQ-C30 questionnaire is suitable for the acquisition of the health-related quality of life in formerly critically ill patients. Health-related quality of life is severely impaired after mechanical ventilation in the intensive care unit. Future studies should consider health related quality of life as a possible study endpoint. PMID: 28175941 [PubMed - as supplied by publisher]
Source: Der Anaesthesist - Category: Anesthesiology Authors: Tags: Anaesthesist Source Type: research

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Source: BMJ Comments - Category: General Medicine Source Type: forums
Source: BMJ Comments - Category: General Medicine Source Type: forums
ConclusionOur results show that fluoroscopic-guided NGT placement is a highly safe and effective procedure for patients with advanced HNC requiring enteral feeding.
Source: Journal of the Formosan Medical Association - Category: General Medicine Source Type: research
Authors: Ren C, Zhang Z, Wang S, Zhu W, Zheng P, Wang W Abstract Metastasis is the main cause of increasing cancer morbidity and mortality. However, the underlying mechanism of cancer metastasis remains largely unknown. In the present study, we identified one circular RNA (circRNA) closely related to the metastasis of colorectal cancer (CRC), namely hsa_circ_0001178. CRC patients with high hsa_circ_0001178 were more prone to have metastatic clinical features, advanced TNM stage and adverse prognosis. Stable knockdown of hsa_circ_0001178 significantly weakened CRC cell migratory and invasive capabilities in vitro as...
Source: Biological Chemistry - Category: Chemistry Tags: Biol Chem Source Type: research
Publication date: Available online 20 November 2019Source: Arab Journal of GastroenterologyAuthor(s): Shogo Nakano, Kosuke Minaga, Yukitaka Yamashita
Source: Arab Journal of Gastroenterology - Category: Gastroenterology Source Type: research
The human genome has been proposed to contribute to interpersonal variability in the way we respond to nutritional intake. However, personalized diets solely based on gene-nutrient interactions have not lived up to their expectations to date. Advances in microbiome research have indicated that a science-based generation of a personalized diet based on a combination of clinical and microbial features may constitute a promising new approach enabling accurate prediction of dietary responses. In addition, scientific advances in our understanding of defined dietary components and their effects on human physiology led to the inc...
Source: Journal of Pediatric Gastroenterology and Nutrition - Category: Gastroenterology Tags: Invited Review Source Type: research
Objectives: Gastroesophageal reflux (GER), excessive crying, and constipation are common gastrointestinal symptoms in infancy of multifactorial origin in which psychosocial stress factors play an important role. The aims of this observational study were to investigate the presence of gastrointestinal symptoms in infants of mothers with or without a history of a psychiatric disorder, their association with maternal depressive symptoms, and the possible mediating role of bonding. Methods: One hundred one mothers with a history of a psychiatric disorder and 60 control mothers were included. Infant gastrointestinal sympto...
Source: Journal of Pediatric Gastroenterology and Nutrition - Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research
Publication date: Available online 21 November 2019Source: Molecular and Cellular EndocrinologyAuthor(s): Chongwen Xu, Junsong Liu, Xiaobao Yao, Yanxia Bai, Qian Zhao, Ruimin Zhao, Bo Kou, Honghui Li, Peng Han, Xuan Wang, Longwei Guo, Zhiwei Zheng, Shaoqiang ZhangAbstractmicroRNA-147b (miR-147b) is a newly identified tumor-related miRNA that is dysregulated in multiple cancer types. Yet, the role of miR-147b in thyroid carcinoma remains unknown. Herein, we found that miR-147b expression was upregulated in thyroid carcinoma tissues and cell lines. miR-147b inhibition decreased the proliferation, colony formation, and invasi...
Source: Molecular and Cellular Endocrinology - Category: Endocrinology Source Type: research
Publication date: Available online 21 November 2019Source: SteroidsAuthor(s): Jin-Jie Li, Xiang-Jian Zhong, Xin Wang, Xi-Miao Yang, Jian-Yu Yue, Xuan Zhang, Jia-Chen Liu, Kai-Qi Wang, Xiao-Ya ShangAbstractUsing a cell-based cytotoxicity assay, two new polyhydroxylated sterols, 16(S),22(S)-epoxy-3β,5α,6β,20(R),23(R),25-hexahydroxy-7-ergostene and 3β,7β,8α,25-tetrahydroxy-5,22E-ergostadiene were isolated from the ethyl acetate portion of the ethanolic extract of Monascus purpureus. Their structures were elucidated by spectroscopic analysis and in comparison with those reported in the literatur...
Source: Steroids - Category: Drugs & Pharmacology Source Type: research
CONCLUSIONS:This study suggests that a PCP in neuro-oncology can produce a high rate of establishing goals of care. A PCP can significantly reduce the cost of care in a value based model. Further study on the impact of palliative care in neuro-oncology seems warranted.
Source: Neuro-Oncology - Category: Cancer & Oncology Authors: Tags: SUPPORTIVE PALLIATIVE CARE Source Type: research
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