Trigeminal Neuralgia Induced by Cobra Venom Leads to Cognitive Deficits Associated with Downregulation of CREB/BDNF Pathway.

CONCLUSIONS: The findings suggest that cognitive impairment caused by cobra venom-induced trigeminal neuralgia is associated with downregulation of the CREB/BDNF pathway in the hippocampus and PFC.Key words: Cognitive impairment, the CREB/BDNF pathway, cobra venom, trigeminal neuralgia, hippocampus, prefrontal cortex, free behavior, Morris water maze. PMID: 28158153 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/28158153?dopt=Abstract

Source: Pain Physician - January 31, 2017 Category: Anesthesiology Authors: Zhang L, Ding X, Wu Z, Qian X, An J, Tian M Tags: Pain Physician Source Type: research