Substrate Ablation of Ventricular Tachycardia: Late Potentials, Scar Dechanneling, Local Abnormal Ventricular Activities, Core Isolation, and Homogenization

Publication date: March 2017 Source:Cardiac Electrophysiology Clinics, Volume 9, Issue 1 Author(s): David F. Briceño, Jorge Romero, Carola Gianni, Sanghamitra Mohanty, Pedro A. Villablanca, Andrea Natale, Luigi Di BiaseTeaser Ventricular arrhythmias are a frequent cause of mortality in patients with ischemic cardiomyopathy and nonischemic cardiomyopathy. Scar-related reentry represents the most common arrhythmia substrate in patients with recurrent episodes of sustained ventricular tachycardia (VT). Initial mapping of scar-related VT circuits is focused on identifying arrhythmogenic tissue. The substrate-based strategies include targeting late potentials, scar dechanneling, local abnormal ventricular activities, core isolation, and homogenization of the scar. Even though substrate-based strategies for VT ablation have shown promising outcomes for patients with structural heart disease related to ischemic cardiomyopathy, the data are scarce for patients with nonischemic substrates.
Source: Cardiac Electrophysiology Clinics - Category: Cardiology Source Type: research