Histone deacetylase inhibitors VPA and TSA induce apoptosis and autophagy in pancreatic cancer cells

ConclusionsFrom our results we conclude that both VPA and TSA can induce pancreatic cancer cell apoptosis and autophagy. VPA appears have a stronger and broader cytotoxic effect than TSA and, thus, may represent a better choice for anti-pancreatic cancer therapy.
Source: Cellular Oncology - Category: Cancer & Oncology Source Type: research