New technical developments for inhaled sedation.

[New technical developments for inhaled sedation]. Anaesthesist. 2017 Jan 31;: Authors: Meiser A, Bomberg H, Volk T, Groesdonk HV Abstract The circle system has been in use for more than 100 years, whereas the first clinical application of an anaesthetic reflector was reported just 15 years ago. In the circle system, all breathing gas is rebreathed after carbon dioxide absorption. A reflector, on the other hand, with the breathing gas flowing to and fro, specifically retains the anaesthetic during expiration and resupplies it during the next inspiration. A high reflection efficiency (number of molecules resupplied/number of molecules exhaled, RE 80-90%) decreases consumption. In analogy to the fresh gas flow of a circle system, pulmonary clearance ((1-RE) × minute ventilation) defines the opposition between consumption and control of the concentration.It was not until reflection systems became available that volatile anaesthetics were used routinely in some intensive care units. Their advantages, such as easy handling, and better ventilatory capabilities of intensive care versus anaesthesia ventilators, were basic preconditions for this. Apart from AnaConDa™ (Sedana Medical, Uppsala, Sweden), the new MIRUS™ system (Pall Medical, Dreieich, Germany) represents a second, more sophisticated commercially available system.Organ protective effects, excellent control of sedation, and dose-dependent deep sedation wh...
Source: Der Anaesthesist - Category: Anesthesiology Authors: Tags: Anaesthesist Source Type: research

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CONCLUSIONS: Anesthetic preconditioning is a promising strategy to prevent I-R injury associated with transplantation. Our results suggest that sirtuin 2 is involved in the protective mechanisms of some commonly used anesthetics against I-R damage. PMID: 31726818 [PubMed - as supplied by publisher]
Source: Minerva Urologica e Nefrologica - Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
Recently saw this from Pamela Wible, whos been tracking suicide rates for the past some years. She had 10 names in 2012, now 1363. Anesthesiology as expected is #1 by far. Thought this would be interesting to see for some of you
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Medical Students - MD Source Type: forums
We report successful anaesthetic management of an accidental traumatic rupture of the left main bronchus during surgical dissection in an elderly lady of Carcinoma Oesophagus who underwent a Video Assisted Thoracoscopic surgery (VATS), and was managed by one lung ventilation of the contralateral (right) side manipulating the same DLT and lung protective ventilation.
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
ConclusionsFlow disruptions in robotic abdominal sacrocolpopexy surgery occur about every 6  min. Flow disruption rates are highest during the most complex portions of the surgery. More experienced surgeons have lower flow disruption rates and operate more quickly.
Source: International Urogynecology Journal - Category: OBGYN Source Type: research
ConclusionsLSC is feasible, with equivalent intraoperative complication rates for normal weight, overweight and obese women when performed by experienced laparoscopic urogynaecologists. Given the benefits of a laparoscopic approach in obese women, the authors suggest they should be offered LSC as an option to treat vault prolapse when surgical management is being considered.
Source: International Urogynecology Journal - Category: OBGYN Source Type: research
Children with nearsightedness (myopia) may now benefit from the first contact lens approved by FDA for slowing the progression of the common condition. Until now, traditional eyeglasses and contact lenses available in the United States have only been developed to correct blurred vision (a symptom of myopia), but not for slowing the progression of the condition.  “Today’s approval is the first FDA-approved product to slow the progression of myopia in children, which ultimately could mean a reduced risk of developing other eye problems,”...
Source: MDDI - Category: Medical Devices Authors: Tags: Business Source Type: news
ConclusionThis study suggests that the post-auricular approach is a feasible and less time consuming route for round window drug delivery experiments in Wistar albino rats. Recognition of anatomical landmarks, particularly the facial nerve is the key to surgery.
Source: Journal of Neuroscience Methods - Category: Neuroscience Source Type: research
Conditions:   Drug Effect;   Tooth Extraction Intervention:   Drug: Articaine / EPINEPHrine Cartridge Sponsor:   Universidad de Antioquia Enrolling by invitation
Source: - Category: Research Source Type: clinical trials
Conditions:   Cataract;   Analgesia;   Ophthalmological Disorder Interventions:   Drug: lignocaine;   Procedure: Phacoemulsyfication;   Procedure: Intraocular lens implantation;   Behavioral: Visual Analog Scale for Pain;   Behavioral: Brief Pain Inventory-short form;   Diagnostic Test: Best corrected visual acuity measurment;   Diagnostic Test: Slit-lam p biomicroscopy Sponsor:   Medical University of Lublin Completed
Source: - Category: Research Source Type: clinical trials
Conditions:   Pain;   Regional Anesthesia Morbidity;   Arthroplasty Complications Intervention:   Procedure: Lumbar erector spinae plane block Sponsor:   University of Sao Paulo General Hospital Recruiting
Source: - Category: Research Source Type: clinical trials
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