Trial sequential analysis : Sample size calculation for reliable meta-analyses.

CONCLUSION: The TSA is a suitable tool to minimize the risk of random errors and for a more reliable assessment of the evidence for the results of a meta-analysis. PMID: 28144687 [PubMed - as supplied by publisher]
Source: Der Anaesthesist - Category: Anesthesiology Authors: Tags: Anaesthesist Source Type: research

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Jeffrey A. SingerA new study reported in the November 1, 2019Annals of Emergency Medicine pours more  cold water on the false but persistent narrative that the opioid overdose crisis was caused by doctors prescribing opioids to patients in pain.This prospective cohort study by researchers in the Department of Emergency Medicine at Albert Einstein College of Medicine followed 484 “opioid naïve” patients prescribed opioids for acute pain upon release from the emergency department during a six month period. The statewide prescription drug monitoring program was employed in addition to regular f...
Source: Cato-at-liberty - Category: American Health Authors: Source Type: blogs
Conditions:   Breast Cancer;   Breast Cancer Lymphedema;   Pain;   Pain, Postoperative;   Pain, Chronic;   Mastectomy; Lymphedema;   Breast Surgery Interventions:   Other: Single rehabilitative treatment;   Other: Group rehabilitative treatment Sponsor:   University of Roma La Sapienza Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Overall, higher levels of mindfulness were associated with less pain, fatigue, anxiety, depression and sleep disturbance, according to the study published Nov. 8 in the journal Psycho-Oncology.
Source: WebMD Health - Category: Consumer Health News Source Type: news
Parents may think they’re protecting their kids from pain, but keeping such secrets can do more harm than good.
Source: Washington Post: To Your Health - Category: Consumer Health News Authors: Source Type: news
Conclusion: The CFA and DIF analysis supported the construct validity of the SRMP and its use in an ethnically diverse breast cancer population. These findings provide further evidence of the generalizability for the SRMP, and support its utilization as a psychometrically valid and reliable screening measure of cancer and treatment-related memory difficulties. PMID: 31702413 [PubMed - as supplied by publisher]
Source: Acta Oncologica - Category: Cancer & Oncology Authors: Tags: Acta Oncol Source Type: research
ConclusionThe Redon drain and the new Quadrain drain were not significantly different with respect to duration in the surgical site, post-operative pain, seroma volume and cosmetic result.
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
This study systematically analyzed the anticancer potential of Acridocarpus orientalis (AO), a traditional medicinal plant of the Arabian Peninsula/East Africa known for its anti-inflammatory and pain relief properties. Tests of serial organic fractions from methanolic extracts of its leaves and stems revealed that only some fractions showed anti-proliferative potential with the dichloromethane fraction from leaves (AOD (L)) showing the most cytotoxic effect against both breast (MCF-7 and MDA-MB-231) and cervical (HeLa) cancer cell lines. The n-butanol fraction from the stems (AOB (S)), on the other hand, was more effectiv...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
The aim of this study was to assess the effect of preoperative sleep quality on acute postoperative pain in breast cancer patients. The Pittsburgh Sleep Quality Index questionnaire (PSQI) was used to assess the overall sleep status of women scheduled for unilateral modified radical mastectomy in the past month. Based on the responses, patients were allocated to good sleep group or poor sleep group. Postoperatively, acute pain was assessed using the numerical rating score in the first 24 hours; in addition, the requirement of analgesics and the incidence of postoperative complications were recorded. A total of 108 breas...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Conditions:   Breast Cancer;   Pain, Chronic;   Pain, Postoperative;   Mastectomy; Lymphedema Intervention:   Other: Rehabilitation protocol Sponsor:   University of Roma La Sapienza Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSION: Local and regional anesthetic techniques and intravenous lidocaine lower the incidence of CPSP after certain types of operative procedures. The intravenous administration of lidocaine to prevent CPSP is off label and requires the patient's informed consent. The evidence for the measures presented here is of low to medium quality. PMID: 31130157 [PubMed - in process]
Source: Deutsches Arzteblatt International - Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research
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