Continued midazolam versus diphenhydramine in difficult-to-sedate patients: a randomized double-blind trial

Current guidelines recommend diphenhydramine in patients undergoing endoscopy who are not adequately sedated with a benzodiazepine and opioid combination. Because this practice has not been adequately assessed, we performed a randomized, double-blind trial comparing diphenhydramine to continued midazolam in such patients.

Source: Gastrointestinal Endoscopy - January 30, 2017 Category: Gastroenterology Authors: Hamita Sachar, Nipaporn Pichetshote, Kavitha Nandigam, Keta Vaidya, Loren Laine Source Type: research